$150 million from the Stavros Niarchos Foundation and David Rockefeller launch major campus extension

$150 million from the Stavros Niarchos Foundation and David Rockefeller launch major campus extensionMarc Tessier-Lavigne, president of The Rockefeller University, today announced two leadership pledges of $75 million each from the Stavros Niarchos Foundation and David Rockefeller to launch a major extension of the University’s campus on the East River. Designed by Raphael Viñoly Architects, the project will add two acres to the existing 14 acres of the campus by building over the FDR East River Drive, enabling the creation of several new buildings with state-of-the-art laboratories, administrative space, a conference facility, a dining commons, and an outdoor amphitheater. More »

Research suggests how mosquitoes evolved an attraction to human scent

Research suggests how mosquitoes evolved an attraction to human scentTo understand the evolutionary basis of the mosquito’s attraction to humans, scientists examined the genes that drive preferences of two different subspecies. Their findings suggest that Aedes aegypti aegypti acquired a love for human body odor, a key step in specializing on people. More »

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C. David Allis wins the 2015 Breakthrough Prize in Life Sciences

C. David Allis wins the 2015 Breakthrough Prize in Life Sciences’Allis is recognized for his foundational research on the unexpected regulation of gene activation by modifications to proteins that package DNA, work with implications for many diseases including cancer. The Breakthrough Prize is worth $3 million, making it the richest prize in the life sciences, roughly double the Nobel Prize. More »

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3D deep-imaging advance likely to drive new biological insights

3D deep-imaging advance likely to drive new biological insights’In a significant technical advance, a team of neuroscientists at The Rockefeller University has devised a fast, inexpensive imaging method for probing the molecular intricacies of large biological samples in three dimensions, an achievement that could have far reaching implications in a wide array of basic biological investigations. More »

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Research resolves contradiction over protein’s role at telomeres

Research resolves contradiction over protein’s role at telomeresWhen researchers tagged telomeres, protective ends on chromosomes (green and red), of human cells engineered to lack a particular protein, the telomeres did not attach to one another as some previous studies suggested they would. More »

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Cori Bargmann awarded 2015 Benjamin Franklin Medal

New technique efficiently turns antibodies into highly tuned ‘nanobodies’Rockefeller University neurobiologist Cori Bargmann will receive the 2015 Benjamin Franklin Medal in Life Sciences for contributions that have led to major discoveries elucidating the relationship between genes, neurons, neural circuits and behavior. The award, announced this week, will be presented in April at The Franklin Institute in Philadelphia. More »

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New technique efficiently turns antibodies into highly tuned ‘nanobodies’

New technique efficiently turns antibodies into highly tuned ‘nanobodies’Tiny versions of antibodies latch onto their target molecules, which cellular fibers (red) have been engineered to express. Researchers have developed a new system for identifying the nanobodies with the highest affinity for their targets. More »

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One signal means different things to stem cells versus their progeny

One signal means different things to stem cells versus their progenyWhen researchers shut down hair follicle stem cells’ ability to respond to a protein, the cells began dividing prematurely forming a pocket of new cells (red). The same protein has a different effect on the stem cells’ progeny. More »

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Single gene links susceptibility to rare infections with predisposition to autoimmune disease

Single gene links susceptibility to rare infections with predisposition to autoimmune diseaseWhen scientists scanned the brains of patients who lack a particular immune protein, they saw calcium deposits (center white spots) linked with certain diseases that occur as a result of harmful and unnecessary inflammation. More »

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Atomic map reveals clues to how cholesterol is made

Atomic map reveals clues to how cholesterol is madeAn enzyme embedded in the cell membrane performs a crucial step in the complex process by which cells produce cholesterol. Researchers have examined the enzyme’s structure to better understand how it works. More »

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Newly discovered brain cells explain a prosocial effect of oxytocin

Newly discovered brain cells explain a prosocial effect of oxytocinWhen activated by the ‘love hormone’ oxytocin, a class of star-shaped neurons (left) in the brain’s cortex encourages female mice to take an interest in males, but only when the females are in heat. More »

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Rockefeller neurobiology lab is awarded first-round BRAIN initiative grant

Rockefeller neurobiology lab is awarded first-round BRAIN initiative grantResearchers are developing a technology to remotely turn neurons and other cells on or off. The bright spots represent cells undergoing a change that would enable neurons to fire on command. More »

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‘Programmable’ antibiotic harnesses an enzyme to attack drug-resistant microbes

“Programmable” antibiotic harnesses an enzyme to attack drug-resistant microbesBy co-opting a system bacteria normally use to defend themselves, researchers targeted and killed off colonies of the antibiotic resistant Staph cells on mouse skin. The treatment left behind the drug-susceptible microbes. More »

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Rockefeller postdoc Stephen Brohawn named Blavatnik Award regional finalist

Rockefeller postdoc Stephen Brohawn named Blavatnik Award regional finalistBrohawn, a member of Roderick MacKinnon’s Laboratory of Molecular Neurobiology and Biophysics, studies how proteins called mechanosensitive ion channels sense mechanical forces. He is one of nine finalists from the New York region. More »

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Stanford’s Lucy Shapiro to receive 2014 Pearl Meister Greengard Prize

Stanford's Lucy Shapiro to receive 2014 Pearl Meister Greengard Prize The Rockefeller University has announced that Lucy Shapiro, professor of developmental biology at Stanford University School of Medicine, will receive the 2014 Pearl Meister Greengard Prize. The annual award, which celebrates the achievements of outstanding women in science, will be presented to Shapiro on the Rockefeller campus November 11. More »

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New technique reveals a role for histones in cell division

New technique reveals a role for histones in cell divisionResearchers have found that key aspects of cell division, such as the formation of the support structure (green) for the envelope that surrounds the nucleus, depend on the presence of DNA-organizing proteins known as histones. More »

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Imaging studies open a window on how effective antibodies are formed

Imaging studies open a window on how effective antibodies are formedBy imaging the immune response, researchers have observed how two types of immune cells interact with one another during a critical period following infection in order to prepare the best antibodies and establish long-lasting protection. More »

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Hironori Funabiki promoted to professor

Funabiki’s research has pointed to a role for DNA-packaging proteins known as histones in the formation of structures involved in cell division, with implications for understanding and treating disease. More »

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Research hints at why stress is more devastating for some

Research hints at why stress is more devastating for someSome bounce back from stress, while others struggle with it, even developing anxiety and depression as a result. In experiments with mice, researchers have revealed the molecular origins of this so-called stress gap.
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Discovery reveals how bacteria distinguish harmful versus helpful viruses

Discovery reveals how bacteria distinguish harmful versus helpful virusesViruses can kill bacteria, or viruses can help the microbes by lending them potentially useful genes. New research shows Staph bacteria have an immune system capable of distinguishing dangerous invaders from potentially beneficial ones. More »

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