Yearly Archives: 2012

Proceedings of the National Academy of Sciences USA online: December 31, 2012

Proceedings of the National Academy of Sciences USA online: December 31, 2012 Solubility-based genetic screen identifies RING finger protein 126 as an E3 ligase for activation-induced cytidine deaminase Rebecca K. Delker, Yanjiao Zhou, Alexandros Strikoudis, C. Erec Stebbins and F. … More »

Molecular Cell online: December 22, 2012

Molecular Cell online: December 22, 2012 An H3K36 methylation-engaging tudor motif of polycomb-like proteins mediates PRC2 complex targeting Ling Cai, Scott B. Rothbart, Rui Lu, Bowen Xu, Wei-Yi Chen, Ashutosh Tripathy, Shira Rockowitz, Deyou Zheng, Dinshaw J. Patel, C. David … More »

Molecular Cell online: December 27, 2012

Molecular Cell online: December 27, 2012 Activation of DSB processing requires phosphorylation of CtIP by ATR Shaun E. Peterson, Yinyin Li, Foon Wu-Baer, Brian T. Chait, Richard Baer, Hong Yan, Max E. Gottesman and Jean Gautier

Proceedings of the National Academy of Sciences USA 109: 21319-21324 (12-26-12)

Proceedings of the National Academy of Sciences USA 109: 21319-21324 Reelin is a target of polyglutamine expanded ataxin-7 in human spinocerebellar ataxia type 7 (SCA7) astrocytes Shaun D. McCullough, Xiaojiang Xu, Sharon Y. R. Dent, Stefan  Bekiranov, Robert G. Roederc … More »

Changes in population growth, consumption and farming begin to return former farmlands to nature

Researchers led by Rockefeller’s Jesse Ausubel analyzed factors such as global land use and population growth over the last 50 years. Looking at the production index of all crops of the UN’s Food and Agriculture Organization, they found that from 1961 to 2009 land farmed grew by only 12 percent while the index rose about 300 percent.

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Cell 151: 1417-1430 (12-21-12)

Cell 151: 1417-1430 MeCP2 binds to 5hmC enriched within active genes and accessible chromatin in the nervous system Marian Mellén, Pinar Ayata, Scott Dewell, Skirmantas Kriaucionis and Nathaniel Heintz

In the News

Is the Cure for Cancer Inside You?   “In the long struggle that was to come, [Ralph] Steinman would try anything and everything that might extend his life, but he placed his greatest hope in a field he helped create, … More »

In the News

Farmland Peaks, Crop Space to Revert Back to Nature, Report Finds   “Humanity has reached what Rockefeller University scientists, in a new report, call ‘peak farmland.’ In the next half-century, a geographical area more than twice the size of France … More »

In the News

Worried about Underwater Creatures, Scientists Want to Hush the Noisy Oceans   “[O]ceans have actually become very loud due to man-made noise from oil rigs, sonar and ship propellers. And scientists are worried that all that added noise is hurting … More »

Nature 492: 382–386 (12-20-12)

Nature 492: 382–386 FMRP targets distinct mRNA sequence elements to regulate protein expression Manuel Ascano, Neelanjan Mukherjee, Pradeep Bandaru, Jason B. Miller, Jeffrey D. Nusbaum, David L. Corcoran, Christine Langlois, Mathias  Munschauer, Scott Dewell, Markus Hafner, Zev Williams, Uwe Ohler … More »

Proceedings of the National Academy of Sciences USA 109: 21076-21080 (12-18-12)

Proceedings of the National Academy of Sciences USA 109: 21076-21080 Contribution of active hair-bundle motility to nonlinear amplification in the mammalian cochlea Fumiaki Nin, Tobias Reichenbach, Jonathan A. N. Fisher and A. J. Hudspeth

Journal of Experimental Medicine: December 17, 2012

Journal of Experimental Medicine: December 17, 2012 Mechanism of DNA resection during intrachromosomal recombination and immunoglobulin class switching Anne Bothmer, Philipp C. Rommel, Anna Gazumyan, Federica  Polato, Colleen R. Reczek, Matthias F. Muellenbeck, Sonja Schaetzlein, Winfried Edelmann, Phang-Lang Chen, Robert … More »

New neuroscience textbook will be a free reference for students in developing countries

The textbook, conceived and edited by Rockefeller University professor Donald W. Pfaff, is a 3,200 page, five-volume overview of both basic science and clinical issues in modern neuroscience, aimed at premedical, medical and graduate students.
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Nature online: December 12, 2012

Nature online: December 12, 2012 Rapid regulation of depression-related behaviours by control of midbrain dopamine neurons Dipesh Chaudhury, Jessica J. Walsh, Allyson K. Friedman, Barbara Juarez, Stacy M. Ku, Ja Wook Koo, Deveroux Ferguson, Hsing-Chen Tsai, Lisa  Pomeranz, Daniel J. … More »

Nature Methods online: December 9, 2012

Nature Methods online: December 9, 2012 Fast multicolor 3D imaging using aberration-corrected multifocus microscopy Sara Abrahamsson, Jiji Chen, Bassam Hajj, Sjoerd Stallinga, Alexander Y. Katsov, Jan Wisniewski, Gaku Mizuguchi, Pierre Soule, Florian Mueller, Claire Dugast Darzacq, Xavier Darzacq, Carl Wu, … More »

Science 338: 1352-1353 (12-7-12)

Science 338: 1352-1353 Developmental progression to infectivity in Trypanosoma brucei triggered by an RNA-binding protein Nikolay G. Kolev, Kiantra Ramey-Butler, George A. M. Cross, Elisabetta Ullu and Christian Tschudi

Neuron 76: 989-997 (12-6-12)

Neuron 76: 989-997 The spatial pattern of cochlear amplification Jonathan A.N. Fisher, Fumiaki Nin, Tobias Reichenbach, Revathy C.  Uthaiah and A.J. Hudspeth

Charles M. Rice awarded Dautrebande Prize

Rice, head of the Laboratory of Virology and Infectious Disease at Rockefeller, has been awarded the 100,000 euro prize for his description of the molecular and cellular basis of hepatitis C infection in humans.
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Robert Darnell named president of New York Genome Center

Darnell will direct all aspects of the NYGC, including its scientific and research activities, and the recruitment and development of a world-class scientific team in genomic research and medicine. Founded in 2010, the NYGC will be one of the largest genomics research facilities in North America, integrating sequencing, bioinformatics and data management. More »

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Cell 151: 1126-1137 (11-21-12)

Cell 151: 1126-1137 Molecular profiling of activated neurons by phosphorylated ribosome capture Zachary A. Knight, Keith Tan, Kivanc Birsoy, Sarah Schmidt, Jennifer L. Garrison, Robert W. Wysocki, Ana Emiliano, Mats I.  Ekstrand and Jeffrey M. Friedman