Yearly Archives: 2013

Nature Medicine online: December 22, 2013

Nature Medicine online: December 22, 2013 Host-cell sensors for Plasmodium activate innate immunity against liver-stage infection Peter Liehl, Vanessa Zuzarte-Luís, Jennie Chan, Thomas Zillinger, Fernanda Baptista, Daniel Carapau, Madlen Konert, Kirsten K. Hanson, Céline Carret, Caroline Lassnig, Mathias Müller, Ulrich … More »

Molecular Psychiatry online: December 17, 2013

Molecular Psychiatry online: December 17, 2013 Hippocampal gene expression changes underlying stress sensitization and recovery J.D. Gray, T.G. Rubin, R.G. Hunter and B.S. McEwen

Proceedings of the National Academy of Sciences USA 110: 20455-20460 (12-17-13)

Proceedings of the National Academy of Sciences USA 110: 20455-20460 Flavin reduction activates Drosophila cryptochrome Anand T. Vaidya, Deniz Top, Craig C. Manahan, Joshua M. Tokuda, Sheng Zhang, Lois Pollack, Michael W. Young and Brian R. Crane

Molecular Cell 52: 734-45 (12-12-13)

Molecular Cell 52: 734-45 Autoinhibition and polo-dependent multisite phosphorylation restrict activity of the histone H3 kinase haspin to mitosis Cristina Ghenoiu, Michael S. Wheelock and Hironori Funabiki

Science 342: 1254-1258 (12-6-13)

Science 342: 1254-1258 MicroRNA-128 governs neuronal excitability and motor behavior in mice Chan Lek Tan, Joshua L. Plotkin, Morten T. Venø, Melanie von Schimmelmann, Philip Feinberg, Silas Mann, Annie Handler, Jørgen Kjems, D. James Surmeier, Dónal O’Carroll, Paul Greengard and … More »

In the News

Pearl Meister Greengard prize winner followed a gut feeling for 16 years   “Pediatric neurologist and neuroscientist Huda Y. Zoghbi won Rockefeller University’s 10th annual Pearl Meister Greengard Prize, which on Thursday night she attributed in part to following ‘a … More »

Large-scale survey of clinical research participants shows mostly positive experiences

Although many participants gave high marks to the research teams’ trustworthiness and ability to explain their protocols, the survey also revealed that a sizable minority did not feel completely prepared for the study. The results suggest aspects of the participant experience that researchers may be able to address. More »

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Michael A. Foley named director of Tri-I Therapeutics Discovery Institute

An accomplished chemist and entrepreneur with more than 25 years of industry and academic experience, Foley has been named director of a pioneering early stage drug discovery initiative formed jointly with Weill Cornell Medical College and Memorial Sloan-Kettering Cancer Center formed in October. More »

In the News

Biology’s coefficient: Joel Cohen uses the tools of mathematics to deconstruct questions of life   “That study of Earth’s human population is only a drop in the bucket of the diverse, seemingly disparate, subjects that Cohen has addressed in his … More »

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Genes and Development online: November 27, 2013

Genes and Development online: November 27, 2013 Role of SWI/SNF in acute leukemia maintenance and enhancer-mediated Myc regulation Junwei Shi, Warren A. Whyte, Cinthya J. Zepeda-Mendoza, Joseph P. Milazzo, Chen Shen, Jae-Seok Roe, Jessica L. Minder, Fatih Mercan, Eric Wang, … More »

Nature online: November 27, 2013

Nature online: November 27, 2013 Pan-viral specificity of IFN-induced genes reveals new roles for cGAS in innate immunity John W. Schoggins, Donna A. MacDuff, Naoko Imanaka, Maria D. Gainey, Bimmi Shrestha, Jennifer L. Eitson, Katrina B. Mar, R. Blake Richardson, … More »

Proceedings of the National Academy of Sciences USA online: November 26, 2013

Proceedings of the National Academy of Sciences USA online: November 26, 2013 Nfatc1 orchestrates aging in hair follicle stem cells Brice E. Keyes, Jeremy P. Segal, Evan Heller, Wen-Hui Lien, Chiung-Ying Chang, Xingyi Guo, Dan S. Oristian, Deyou Zheng and … More »

Proceedings of the National Academy of Sciences USA 110: 19501-19506 (11-26-13)

Proceedings of the National Academy of Sciences USA 110: 19501-19506 Antitumor activities of agonistic anti-TNFR antibodies require differential FcγRIIB coengagement in vivo Fubin Li and Jeffrey V. Ravetch

Journal of Experimental Medicine online: November 25, 2013

Journal of Experimental Medicine online: November 25, 2013 Broadly neutralizing antibodies that inhibit HIV-1 cell to cell transmission Marine Malbec, Françoise Porrot, Rejane Rua, Joshua Horwitz, Florian Klein, Ari Halper-Stromberg, Johannes F. Scheid, Caroline Eden, Hugo Mouquet, Michel C. Nussenzweig … More »

Nature Structural Molecular Biology online: November 24, 2013

Nature Structural Molecular Biology online: November 24, 2013 The human cap-binding complex is functionally connected to the nuclear RNA exosome Peter Refsing Andersen, Michal Domanski, Maiken S. Kristiansen, Helena Storvall, Evgenia Ntini, Celine Verheggen, Aleks Schein, Jakob Bunkenborg, Ina Poser, … More »

Nature Neuroscience online: November 24, 2013

Nature Neuroscience online: November 24, 2013 Stress and CRF gate neural activation of BDNF in the mesolimbic reward pathway Jessica J. Walsh, Allyson K. Friedman, Haosheng Sun, Elizabeth A. Heller, Stacy M. Ku, Barbara Juarez, Veronica L. Burnham, Michelle S. … More »

Cell 155: 1034-1048 (11-21-13)

Cell 155: 1034-1048 Affinity proteomics reveals human host factors implicated in discrete stages of LINE-1 retrotransposition Martin S. Taylor, John LaCava, Paolo Mita, Kelly R. Molloy, Cheng Ran Lisa Huang, Donghui Li, Emily M. Adney, Hua Jiang, Kathleen H. Burns, … More »

Journal of Experimental Medicine 210: 2739-2753 (11-18-13)

Journal of Experimental Medicine 210: 2739-2753 Naive and memory human B cells have distinct requirements for STAT3 activation to differentiate into antibody-secreting plasma cells Elissa K. Deenick, Danielle T. Avery, Anna Chan, Lucinda J. Berglund, Megan L.  Ives, Leen Moens, … More »

Proceedings of the National Academy of Sciences USA online: November 11, 2013

Proceedings of the National Academy of Sciences USA online: November 11, 2013 Phage T7 Gp2 inhibition of Escherichia coli RNA polymerase involves misappropriation of σ70 domain 1.1 Brian Bae, Elizabeth Davis, Daniel Brown, Elizabeth A. Campbell, Sivaramesh Wigneshweraraj and Seth … More »

Cell 155: 881-893 (11-7-13)

Cell 155: 881-893 Opposing dopaminergic and GABAergic neurons control the duration and persistence of copulation in Drosophila Michael A. Crickmore and Leslie B. Vosshall