An unexpected origin for calming immune cells in the gut

An unexpected origin for calming immune cells in the gutWithin the gut, the immune system must strike a perfect balance between protecting our bodies from infection and not overreacting to harmless foreign entities, including food. A new study explores the origins of a type of immune cell that appears to keep inflammatory responses in check. More »

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Michel C. Nussenzweig honored with the 2016 Robert Koch Award

Michel C. Nussenzweig honored with the 2016 Robert Koch AwardGiven by the Robert Koch Foundation, the annual award is one of Germany’s most prestigious scientific prizes, honoring extraordinary accomplishments in infectious disease research. Nussenzweig will share the €100,000 prize with Alberto Mantovani of Humanitas University for their achievements in immunology. More »

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New faculty member investigates how cells respond to mechanical forces

Gregory Alushin will relocate his lab to Rockefeller early next yearBiophysicist Gregory Alushin studies how cells use their structural filaments to respond to forces generated as the cells move about, or by movements in the surrounding tissue. He will relocate his lab to Rockefeller early next year. More »

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Tri-Institutional Therapeutics Discovery Institute expands focus to include antibody drug discovery research

Tri-Institutional Therapeutics Discovery Institute expands focus to include antibody drug discovery researchThe Tri-I TDI, a partnership established in 2013 to expedite early-stage drug discovery of innovative new small molecule therapies, announced today that it will expand its scope to support the development of antibody drug discovery. More »

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Installation of River Campus structure begins with delivery of first of 19 prefabricated modules

Installation of River Campus structure begins with delivery of first of 19 prefabricated modulesOne of the largest barge-mounted cranes on the East Coast will lift the extension’s structural skeleton into place, one section at a time. For safety reasons, the FDR Drive and East River Esplanade will be closed during lift operations, which will occur this summer during overnight hours. More »

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Rockefeller’s annual science festival draws hundreds of young explorers and their families

Science SaturdayOn a recent Saturday, the Rockefeller campus was transformed into a vast science exhibit with more than 35 interactive stations. Each year, this popular event draws families from across New York City to experience the authentic process of science. More »

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31 students receive Ph.D.s at Rockefeller’s 58th convocation

Rockefeller University has graduated 31 new scientists, who received their doctoral degrees from their mentors in a tradition dating back to the university’s first commencement ceremony, in 1959. Honorary doctor of science degrees were also awarded to four esteemed researchers: James Allison, Max Cooper, Suzanne Cory, and Alice Dautry-Varsat. More »

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Heilbrunn Center announces recipients of its 2016 Nurse Scholar Awards

The winners’ projects will focus on teaching women with cancer how to advocate for their health, answering key questions about eating behavior and obesity, addressing the needs of critically ill patients and their families, helping the parents of sick children make medical decisions, and examining brain–gut interactions in gastrointestinal illness. More »

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New faculty member investigates how genes are born and proliferate

Li ZhaoAn evolutionary biologist, Li Zhao is interested in how new genes arise and spread within a population. She will join the faculty in March 2017 as an assistant professor. More »

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New mouse models give a boost to the development of cancer immunotherapies

New mouse models give a boost to the development of cancer immunotherapiesA new cancer treatment called CD40 antibody has yielded disappointing results when tested in clinical trials, failing to mobilize patients’ immune system against tumors the way it was expected to. But a recent study offers clues about how this experimental drug might be optimized to fulfill its potential. More »

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Do artificial sweeteners live up to the promise of sweetness without harm? An ongoing clinical study investigates

Do artificial sweeteners live up to the promise of sweetness without harm? An ongoing clinical study investigatesScientists suspect that aspartame and other artificial sweeteners can lead to lasting, metabolic disruptions when consumed frequently, by activating specific receptors in the intestine. A clinical study is now enrolling volunteer soda drinkers to test the hypothesis. More »

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Researchers uncover how “silent” genetic changes drive cancer

New insights into muscular dystrophy point to potential treatment avenuesSmall molecules called tRNA, whose job is to help translate genes into proteins, are not usually considered important for understanding the causes of disease. But a new study shows that fluctuations in some tRNAs may in fact influence the progression of breast cancer. More »

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New insights into muscular dystrophy point to potential treatment avenues

New insights into muscular dystrophy point to potential treatment avenuesCertain stem cells in our bodies have the potential to turn into either fat or muscle. Experiments in mice suggest prospective drugs that manipulate these cells’ fate could make it possible to relieve many of the symptoms of muscular dystrophy. More »

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Researchers find new signs of stress damage in the brain, plus hope for prevention

Researchers find new signs of stress damage in the brain, plus hope for preventionNew research shows that when mice experience chronic stress, neurons within part of their brain’s fear and anxiety center, the amygdala, retract. It also suggests how such changes could be prevented. More »

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New technique captures the activity of an entire brain in a snapshot

New technique captures the activity of an entire brain in a snapshot With a new imaging tool, scientists are able to measure the activity of all the neurons in a mouse brain with unmatched precision. The method is widely applicable for studying how the brain functions both under normal conditions and in disease. More »

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New method gives scientists a better look at how HIV infects and takes over its host cells

New method gives scientists a better look at how HIV infects and takes over its host cellsA research team wanted to know how HIV uses its tiny genome to manipulate our cells, gain entry, and replicate—all while escaping the immune system. They’ve spent a decade developing an experimental approach that finally is yielding answers. More »

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Rockefeller tops global ranking of scientific impact

Rockefeller tops global ranking of scientific impactRockefeller has the highest percentage of frequently cited scientific publications among 842 leading universities worldwide, according to a survey created by the Center for Science and Technology Studies of Leiden University. The ranking is based on publications indexed in a Thomson Reuters database between 2011 and 2014. More »

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Scientists find evidence that cancer can arise from changes in the proteins that package DNA

Scientists find evidence that cancer can arise from changes in the proteins that package DNAMutations in histones, the proteins that shield and package DNA, have been linked to many types of cancer, but their role in promoting disease has not been clear. Now, for the first time, scientists have found that a change to the structure of a histone can trigger a tumor on its own. More »

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C. David Allis receives the 2016 Gruber Genetics Prize

C. David Allis receives the 2016 Gruber Genetics PrizeAllis shares the award with Michael Grunstein of UCLA for identifying the critical role of histones and histone modification in regulating gene activity. The prize is awarded by The Gruber Foundation of Yale University and honors scientists whose work inspires fundamental shifts in knowledge and culture. More »

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Torsten Wiesel wins Karolinska Institute’s Jubilee Gold Medal

Torsten Wiesel wins Karolinska Institute’s Jubilee Gold MedalWiesel is celebrated with the medical university’s Jubilee Gold Medal for his extraordinary contributions to the Swedish scientific community and to Karolinska itself. The Karolinska Institute, one of the world’s leading medical universities, will present Wiesel with the medal at a ceremony on May 13. More »

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