Antibody therapy opens door to potential new treatment for HIV

Antibody Therapy Opens Door to Potential New Treatment for HIVResearchers are developing an antibody-based drug that may provide a better strategy for long-term control of HIV. New results from a clinical trial suggest that a single dose of a so-called broadly neutralizing antibody enables patients’ immune systems to better fight the virus. More »

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Richard P. Lifton named 11th president of The Rockefeller University

Richard P. LiftonThe Rockefeller University today announced that its Board of Trustees has elected Richard P. Lifton to be the 11th president of the university, effective September 1, 2016. Lifton, 62, Sterling Professor of Genetics and chair of the Department of Genetics at Yale University, will succeed Marc Tessier-Lavigne, who is leaving Rockefeller to become Stanford University’s next president. More »

Researchers use new CRISPR-based strategy to replicate disease in cells

An experimental Alzheimer’s drug reverses genetic changes thought to spur the diseaseWith a new strategy they developed, Rockefeller scientists used the CRISPR genome editing system to engineer neurons so they looked like those in the brains of people suffering from Alzheimer’s disease. This development will aid biomedical research by making it easier to create cellular models of disease. More »

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A central clock runs the cell division cycle

A central clock runs the cell division cycleScientists have long known that proteins called cyclins regulate cell division in yeast, but this picture has lately come into question as oscillations in gene expression were posited to run independently in the cell division cycle. Now a new study confirms that cyclins are indeed in control. More »

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New method allows first look at key stage of human development, embryo implantation

New method allows first look at key stage of human development, embryo implantationAlmost nothing is known about the stage of human development called implantation, when the developing embryo attaches to the uterus. Now scientists have devised a method that replicates implantation in an experimental setting, providing a revolutionary system capable of answering basic questions about our own development. More »

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Nathaniel Heintz and Stanislas Leibler elected to the National Academy of Sciences

Nathanial Heintz and Stanislas Leibler elected to the National Academy of SciencesHeintz, who studies the inner workings of the mammalian brain, and Leibler, who explores questions related to how simple genetic and biochemical networks function, are among the new members and foreign associates to be inducted into the Academy. With Heintz and Leibler’s election, Rockefeller now boasts 37 members or foreign associates of the National Academy of Sciences among its current faculty.

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Charles Rice wins Belgium’s highest scientific prize

Charles Rice wins Belgium’s highest scientific prizeRice has received the 2016 InBev-Baillet Latour Health Prize for his fundamental discoveries in the field of infectious diseases. The award, given by the Baillet Latour Fund to recognize outstanding contributions in biomedical research for the benefit of human health, is Belgium’s most important scientific prize. More »

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An experimental Alzheimer’s drug reverses genetic changes thought to spur the disease

An experimental Alzheimer’s drug reverses genetic changes thought to spur the diseaseWhen given to old rats, riluzole reversed many age-related changes that occur in a brain region key to learning and memory. This drug also produced effects opposing those seen in the brains of Alzheimer’s patients. More »

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Mice engineered with rare kidney disease provide new insights about how cells repair broken DNA

Mice engineered with rare kidney disease provide new insights about how cells repair broken DNAMutations in many genes involved in a certain type of DNA repair cause a rare anemia, but one such gene has been shown to cause kidney disease instead. By eliminating this unique gene in mice, scientists hope to show how and why it has such different effects. More »

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A common brain cell shapes the nervous system in unexpected ways

A common brain cell shapes the nervous system in unexpected waysGlial cells nourish, protect, and support neurons, but their role is far from passive. A new study shows how they can change the shape of nerve endings and distinguish between the different types of neurons they encase. More »

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A newly discovered way for cells to die

A newly discovered way for cells to dieIn studying how worms develop from larvae into adults, scientists have discovered a previously unknown process in which cells are programmed to die. The findings might have implications for understanding some diseases, including neurodegenerative disorders. More »

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Global ranking places Rockefeller ahead of 1,300 universities in two key measures of scientific impact

Rockefeller ahead of 1,300 universities in two key measures of scientific impactRankings released by the European Commission–funded U-Multirank survey place Rockefeller in the top spot in categories related to the impact of its research and the transfer of knowledge to the private sector. The results incorporate data from over 1,300 institutions in more than 90 countries. More »

Sweet tooth? Flies have it too—and new research explains how they know what to eat and when to stop

Sweet tooth? Flies have it too—and new research explains how they know what to eat and when to stopIn studying the eating behavior of fruit flies, scientists have discovered a set of throat neurons that regulate food intake based on how hungry the flies are and whether they’ve had enough sugar. A similar neural circuit may exist in vertebrates, like us. More »

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Using magnetic forces to control neurons, study finds the brain plays key role in glucose metabolism

Using magnetic forces to control neurons, study finds the brain plays key role in glucose metabolismA new tool to control neurons in mice avoids the downfalls of current methods by using magnetic forces to remotely control the flow of ions into specifically targeted cells. Applying this method to a group of neurons in the hypothalamus, researchers found that the brain plays a surprisingly vital role in maintaining blood glucose levels. More »

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Parasites reveal how evolution has molded an ancient nuclear structure

Parasites reveal how evolution has molded an ancient nuclear structureThe architecture of the nuclear pore complex is similar in humans and yeast, suggesting that it had been established over a billion years ago. But new research in a simple parasite, the trypanosome, indicates that it has actually been evolving steadily. More »

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Jeffrey Friedman receives the 2016 Harrington Prize for Innovation in Medicine

Jeffrey Friedman receives the 2016 Harrington Prize for Innovation in MedicineThe award, given by the American Society for Clinical Investigation and the Harrington Discovery Institute, honors those who advance science with achievements notable for innovation, creativity, and potential for clinical application. Friedman is being recognized for his discovery of leptin. More »

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Mayor de Blasio visits Rockefeller for tour and biotech conference

Mayor de Blasio visits Rockefeller for tour and biotech conferenceIn addition to serving as host for a life sciences roundtable, Rockefeller president Marc Tessier-Lavigne led mayor de Blasio on a tour of the campus, introduced him to members of his laboratory, and outlined plans for the new Stavros Niarchos Foundation–David Rockefeller River Campus. More »

A virus common among livestock depends on a microRNA to replicate

A virus common among livestock depends on a micro-RNA to replicate Increasingly, scientists are finding that small RNA molecules might be effective targets for antiviral drugs. Using a new screening method, Rockefeller researchers now show that a number of RNA viruses need access to micro-RNAs produced by their host cells to replicate. More »

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Barry Coller receives the 2016 Gill Award for outstanding contributions to cardiovascular research

Barry Coller receives the 2016 Gill Award for outstanding contributions to cardiovascular researchThis award, given by the University of Kentucky Gill Heart Institute, honors Coller for work that has made a lasting impact on the understanding of cardiovascular biology and disease. Coller studies molecular interactions between blood cells and blood vessels, as well as therapies for diseases such as heart attack and stroke. More »

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New findings suggest severe tornado outbreaks are increasingly common

New findings suggest severe tornado outbreaks are increasingly commonTornado outbreaks, in which multiple tornadoes arise within a limited time, are incredibly damaging. New research suggests that the number of tornadoes per outbreak has increased over the past 60 years, and that the likelihood of future extreme events is growing. More »

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