Category Archives: Research Update

Nat Immunol 2014 Jul 21

Nature Immunology online: July 21, 2014 Type I and type II Fc receptors regulate innate and adaptive immunity Andrew Pincetic, Stylianos Bournazos, David J DiLillo, Jad Maamary, Taia T. Wang, Rony Dahan, Benjamin-Maximillian Fiebiger and Jeffrey V. Ravetch

Cell 158, 300–313

Cell 158, 300–313 Crosstalk between Muscularis Macrophages and Enteric Neurons Regulates Gastrointestinal Motility Paul Andrew Muller, Balázs Koscsó, Gaurav Manohar Rajani, Korey Stevanovic, Marie-Luise Berres, Daigo Hashimoto, Arthur Mortha, Marylene Leboeuf, Xiu-Min Li, Daniel Mucida, E. Richard Stanley, Stephanie Dahan, … More »

Nature Cell Biology online July 13, 2014

Nature Cell Biology online July 13, 2014 Par3-mInsc and Gαi3 cooperate to promote oriented epidermal cell divisions through LGN Scott E. Williams, Lyndsay A. Ratliff, Maria Pia Postiglione, Juergen A. Knoblich and Elaine Fuchs

Nature online: July 9, 2014

Nature online: July 9, 2014 Metastasis-suppressor transcript destabilization through TARBP2 binding of mRNA hairpins | Newswire Hani Goodarzi, Steven Zhang, Colin G. Buss, Lisa Fish, Saeed Tavazoie and Sohail F. Tavazoie

Impaired TrkB Receptor Signaling Underlies Corticostriatal Dysfunction in Huntington’s Disease

Neuron 83(1):178-88 Impaired TrkB Receptor Signaling Underlies Corticostriatal Dysfunction in Huntington’s Disease Joshua L. Plotkin, Michelle Day, Jamys D. Peterson, Zhong Xie, Geraldine J. Kress, Igor Rafalovich, Jyothisri Kondapalli, Tracy S. Gertler, Marc Flajolet, Paul Greengard, Mihaela Stavarache, Michael G. … More »

The kinesin-4 protein Kif7 regulates mammalian Hedgehog signalling by organizing the cilium tip compartment (June 22, 2014)

Nature Cell Biology online: June 22, 2014 The kinesin-4 protein Kif7 regulates mammalian Hedgehog signalling by organizing the cilium tip compartment Mu He, Radhika Subramanian, Fiona Bangs, Tatiana Omelchenko, Karel F. Liem Jr, Tarun M. Kapoor & Kathryn V. Anderson

Science 344, 1401-1405

Science 344, 1401-1405 | Newswire HIV-1–induced AIDS in monkeys Theodora Hatziioannou,Gregory Q. Del Prete, Brandon F. Keele, Jacob D. Estes, Matthew W. McNatt, Julia Bitzegeio, Alice Raymond, Anthony Rodriguez, Fabian Schmidt, C. Mac Trubey, Jeremy Smedley, Michael Piatak Jr., Vineet … More »

Netrin-1 controls sympathetic arterial innervation

Journal of Clinical Investigation online: June 15, 2014 Netrin-1 controls sympathetic arterial innervation Isabelle Brunet, Emma Gordon, Jinah Han, Brunella Cristofaro, Dong Broqueres-You, Chun Liu, Karine Bouvrée, Jiasheng Zhang, Raquel del Toro, Thomas Mathivet, Bruno Larrivée, Julia Jagu, Laurence Pibouin-Fragner, Luc … More »

DrugTargetSeqR: a genomics- and CRISPR-Cas9-based method to analyze drug targets

Nature Chemical Biology online: June 15, 2014 DrugTargetSeqR: a genomics- and CRISPR-Cas9-based method to analyze drug targets Corynn Kasap, Olivier Elemento and Tarun M. Kapoor

Science online: May 29, 2014

Science online: May 29, 2014 Structures of netrin-1 bound to two receptors provide insight into its axon guidance mechanism Kai Xu, Zhuhao Wu, Nicolas Renier, Alexander Antipenko, Dorothea Tzvetkova-Robev, Yan Xu, Maria Minchenko, Vincenzo Nardi-Dei, Kanagalaghatta R. Rajashankar, Juha Himanen, … More »

Nature 509: 637–640 (14-5-29)

Nature 509: 637–640 Clonal selection in the germinal centre by regulated proliferation and hypermutation Alexander D. Gitlin, Ziv Shulman and Michel C. Nussenzweig

Cell 157: 1230-1242 (14-5-22)

Cell 157: 1230-1242 Molecular profiling of neurons based on connectivity Mats I. Ekstrand, Alexander R. Nectow, Zachary A. Knight, Kaamashri N. Latcha, Lisa E. Pomeranz and Jeffrey M. Friedman

Proceedings of the National Academy of Sciences USA 111: 7325-7330 (14-05-20)

Proceedings of the National Academy of Sciences USA 111: 7325-7330 Histone variant H3.3 is an essential maternal factor for oocyte reprogramming Duancheng Wen, Laura A. Banaszynski, Ying Liu, Fuqiang Geng, Kyung-Min Noh, Jenny Xiang, Olivier Elemento, Zev Rosenwaks, C. David … More »

Journal of Experimental Medicine online: May 12, 2014

Journal of Experimental Medicine online: May 12, 2014 A novel Aβ-fibrinogen interaction inhibitor rescues altered thrombosis and cognitive decline in Alzheimer’s disease mice Hyung Jin Ahn, J. Fraser Glickman, Ka Lai Poon, Daria  Zamolodchikov, Odella C. Jno-Charles, Erin H. Norris … More »

Journal of Experimental Medicine 211(6):1049-62

Journal of Experimental Medicine 211(6):1049-62 A novel Aβ-fibrinogen interaction inhibitor rescues altered thrombosis and cognitive decline in Alzheimer’s disease mice Hyung Jin Ahn, J. Fraser Glickman, Ka Lai Poon, Daria Zamolodchikov, Odella C. Jno-Charles, Erin H. Norris and Sidney Strickland

Cell 157: 935-949 (14-5-8)

Cell 157: 935-949 Transit-amplifying cells orchestrate stem cell activity and tissue regeneration Ya-Chieh Hsu, Lishi Li and Elaine Fuchs  

Neuron 82: 682-694 (14-5-7)

Neuron 82: 682-694 Incremental integration of global contours through interplay between visual cortical areas Minggui Chen, Yin Yan, Xiajing Gong, Charles D. Gilbert, Hualou Liang and Wu Li

Proceedings of the National Academy of Sciences USA online: April 28, 2014

Proceedings of the National Academy of Sciences USA online: April 28, 2014 Structure of the branched intermediate in protein splicing Zhihua Liu, Silvia Frutos, Matthew J. Bick, Miquel Vila-Perelló, Galia T. Debelouchina, Seth A. Darst and Tom W. Muir

Cell 157: 636-650 (14-4-24)

Cell 157: 636-650 Human CLP1 mutations alter tRNA biogenesis, affecting both peripheral and central nervous system function Ender Karaca, Stefan Weitzer, Davut Pehlivan, Hiroshi  Shiraishi, Tasos Gogakos, Toshikatsu Hanada, Shalini N. Jhangiani, Wojciech Wiszniewski, Marjorie Withers, Ian M. Campbell, Serkan … More »

Proceedings of the National Academy of Sciences USA online: April 24, 2014

Proceedings of the National Academy of Sciences USA online: April 24, 2014 A model for the generation and transmission of variations in evolution Olivier Rivoire and Stanislas Leibler