Category Archives: Research Update

Science online: May 29, 2014

Science online: May 29, 2014 Structures of netrin-1 bound to two receptors provide insight into its axon guidance mechanism Kai Xu, Zhuhao Wu, Nicolas Renier, Alexander Antipenko, Dorothea Tzvetkova-Robev, Yan Xu, Maria Minchenko, Vincenzo Nardi-Dei, Kanagalaghatta R. Rajashankar, Juha Himanen, … More »

Nature 509: 637–640 (14-5-29)

Nature 509: 637–640 Clonal selection in the germinal centre by regulated proliferation and hypermutation Alexander D. Gitlin, Ziv Shulman and Michel C. Nussenzweig

Cell 157: 1230-1242 (14-5-22)

Cell 157: 1230-1242 Molecular profiling of neurons based on connectivity Mats I. Ekstrand, Alexander R. Nectow, Zachary A. Knight, Kaamashri N. Latcha, Lisa E. Pomeranz and Jeffrey M. Friedman

Proceedings of the National Academy of Sciences USA 111: 7325-7330 (14-05-20)

Proceedings of the National Academy of Sciences USA 111: 7325-7330 Histone variant H3.3 is an essential maternal factor for oocyte reprogramming Duancheng Wen, Laura A. Banaszynski, Ying Liu, Fuqiang Geng, Kyung-Min Noh, Jenny Xiang, Olivier Elemento, Zev Rosenwaks, C. David … More »

Journal of Experimental Medicine online: May 12, 2014

Journal of Experimental Medicine online: May 12, 2014 A novel Aβ-fibrinogen interaction inhibitor rescues altered thrombosis and cognitive decline in Alzheimer’s disease mice Hyung Jin Ahn, J. Fraser Glickman, Ka Lai Poon, Daria  Zamolodchikov, Odella C. Jno-Charles, Erin H. Norris … More »

Cell 157: 935-949 (14-5-8)

Cell 157: 935-949 Transit-amplifying cells orchestrate stem cell activity and tissue regeneration Ya-Chieh Hsu, Lishi Li and Elaine Fuchs  

Neuron 82: 682-694 (14-5-7)

Neuron 82: 682-694 Incremental integration of global contours through interplay between visual cortical areas Minggui Chen, Yin Yan, Xiajing Gong, Charles D. Gilbert, Hualou Liang and Wu Li

Proceedings of the National Academy of Sciences USA online: April 28, 2014

Proceedings of the National Academy of Sciences USA online: April 28, 2014 Structure of the branched intermediate in protein splicing Zhihua Liu, Silvia Frutos, Matthew J. Bick, Miquel Vila-Perelló, Galia T. Debelouchina, Seth A. Darst and Tom W. Muir

Cell 157: 636-650 (14-4-24)

Cell 157: 636-650 Human CLP1 mutations alter tRNA biogenesis, affecting both peripheral and central nervous system function Ender Karaca, Stefan Weitzer, Davut Pehlivan, Hiroshi  Shiraishi, Tasos Gogakos, Toshikatsu Hanada, Shalini N. Jhangiani, Wojciech Wiszniewski, Marjorie Withers, Ian M. Campbell, Serkan … More »

Proceedings of the National Academy of Sciences USA online: April 24, 2014

Proceedings of the National Academy of Sciences USA online: April 24, 2014 A model for the generation and transmission of variations in evolution Olivier Rivoire and Stanislas Leibler

Cell 157: 420-432 (14-4-10)

Cell 157: 420-432 Asymmetric friction of nonmotor MAPs can lead to their directional motion in active microtubule networks Scott Forth, Kuo-Chiang Hsia, Yuta Shimamoto and Tarun M. Kapoor

Proceedings of the National Academy of Sciences USA 111: 1393-1401 (14-4-8)

Proceedings of the National Academy of Sciences USA 111: 1393-1401 Dynamic gene expression by putative hair-cell progenitors during regeneration in the zebrafish lateral line Aaron B. Steiner, Taeryn Kim, Victoria Cabot and A. J. Hudspeth

Nature Genetics online: April 6, 2014

Nature Genetics online: April 6, 2014 Genomic analysis of diffuse intrinsic pontine gliomas identifies three molecular subgroups and recurrent activating ACVR1 mutations Pawel Buczkowicz, Christine Hoeman, Patricia Rakopoulos, Sanja Pajovic, Louis Letourneau, Misko Dzamba, Andrew Morrison, Peter Lewis, Eric Bouffet, … More »

Nature Chemical Biology online: March 30, 2014

Nature Chemical Biology online: March 30, 2014 Lysine 2-hydroxyisobutyrylation is a widely distributed active histone mark Lunzhi Dai, Chao Peng, Emilie Montellier, Zhike Lu, Yue Chen, Haruhiko Ishii, Alexandra Debernardi, Thierry Buchou, Sophie Rousseaux, Fulai Jin, Benjamin R. Sabari, Zhiyou … More »

Science 343: 1370-1372 (14-3-21)

Science 343: 1370-1372 Humans can discriminate more than 1 trillion olfactory stimuli C. Bushdid, M. O. Magnasco, L. B. Vosshall and A. Keller

Molecular Psychiatry online: March 11, 2014

Molecular Psychiatry online: March 11, 2014 Preliminary evidence that early reduction in p11 levels in natural killer cells and monocytes predicts the likelihood of antidepressant response to chronic citalopram P. Svenningsson, L. Berg, D. Matthews, D. F. Ionescu, E. M. … More »

Science 343: 1151-1154 (14-3-7)

Science 343: 1151-1154 Long-acting integrase inhibitor protects macaques from intrarectal simian/human immunodeficiency virus Chasity D. Andrews, William R. Spreen, Hiroshi Mohri, Lee Moss, Susan Ford, Agegnehu Gettie, Kasi Russell-Lodrigue, Rudolf P. Bohm, Cecilia Cheng-Mayer, Zhi Hong, Martin Markowitz and David … More »

Proceedings of the National Academy of Sciences USA online: March 5, 2014

Proceedings of the National Academy of Sciences USA online: March 5, 2014 Molecular adaptations of striatal spiny projection neurons during levodopa-induced dyskinesia Myriam Heiman, Adrian Heilbut,Veronica Francardo, Ruth Kulicke, Robert J.  Fenster, Eric D. Kolaczyk, Jill P. Mesirov, Dalton J. … More »

Proceedings of the National Academy of Sciences USA 111: 3614-3619 (14-3-4)

Proceedings of the National Academy of Sciences USA 111: 3614-3619 Mechanosensitivity is mediated directly by the lipid membrane in TRAAK and TREK1 K+ channels Stephen G. Brohawn, Zhenwei Su and Roderick MacKinnon

Proceedings of the National Academy of Sciences USA online: March 3, 2014

Proceedings of the National Academy of Sciences USA online: March 3, 2014 microRNAs are biomarkers of oncogenic human papillomavirus infections Xiaohong Wang, Hsu-Kun Wang, Yang Li, Markus Hafner, Nilam Sanjib  Banerjee, Shuang Tang, Daniel Briskin, Craig Meyers, Louise T. Chow, … More »