Category Archives: Science News

Imaging studies open a window on how effective antibodies are formed

Imaging studies open a window on how effective antibodies are formedBy imaging the immune response, researchers have observed how two types of immune cells interact with one another during a critical period following infection in order to prepare the best antibodies and establish long-lasting protection. More »

Tags: , , , , , , ,

Research hints at why stress is more devastating for some

Research hints at why stress is more devastating for someSome bounce back from stress, while others struggle with it, even developing anxiety and depression as a result. In experiments with mice, researchers have revealed the molecular origins of this so-called stress gap.
More »

Tags: , , , , , , ,

Discovery reveals how bacteria distinguish harmful versus helpful viruses

Discovery reveals how bacteria distinguish harmful versus helpful virusesViruses can kill bacteria, or viruses can help the microbes by lending them potentially useful genes. New research shows Staph bacteria have an immune system capable of distinguishing dangerous invaders from potentially beneficial ones. More »

Tags: , , , , , , , ,

Research explains how cellular guardians of the gut develop

Research explains how cellular guardians of the intestine developA specialized class of immune cell inhabits the thin layer of tissue that lines the intestine. New experiments reveal how these cells arise, sometimes from other mature immune cells. More »

Tags: , , , , ,

Antibodies, together with viral ‘inducers,’ found to control HIV in mice

Antibodies, together with viral ‘inducers,’ found to control HIV in miceA new strategy devised by researchers at Rockefeller University harnesses the power of broadly neutralizing antibodies, along with a combination of compounds that induce viral transcription, in order to attack latent reservoirs of HIV-infected cells in an approach termed ‘shock and kill.’ More »

Tags: , , , , ,

An embryonic cell’s fate is sealed by the speed of a signal

An embryonic cell’s fate is sealed by the speed of a signalEarly in development, chemical signals tell cells whether to turn into muscle, bone, brain or other tissue. By tracking cells’ responses to signals, researchers found the speed at which the signal arrives has an unexpected influence on that decision. More »

Tags: , , , , , ,

Small RNAs in blood may reveal heart injury

SmallBy profiling the small RNAs circulating in the blood of healthy people versus those with heart failure, a research team identified three so-called microRNAs with the potential for use as indicators of injury to heart muscle. More »

Tags: , , ,

Discovery of pro-metastasis protein reveals mysterious link to neurodegeneration

Discovery of pro-metastasis protein reveals mysterious link to neurodegenerationMice injected with metastatic breast cancer cells showed less metastasis when researchers silenced the protein TARBP2 in these cells. TARBP2 appears to promote metastasis in part by blocking suppressor genes, including two linked with neurodegeneration. More »

Tags: , , , , ,

Researchers create the first model of the DNA ‘replication fork’

Researchers create the first model of the DNA ‘replication fork’This new tool promises to allow scientists to explore the as-yet-unknown details of how cells unzip the double-stranded DNA molecule and replicate it, a process crucial to life. More »

Tags: , , ,

Genetically driven gut feelings help female flies choose a mate

Genetically driven gut feelings help female flies choose a mateResearchers at Rockefeller University have determined that the Abdominal-B (Abd-B) gene, previously known as the gene that sculpts the posterior parts of the developing fly, is also important for a complex courtship behavior, at least in the case of female flies. More »

Tags: , , ,

Using geometry, researchers coax human embryonic stem cells to organize themselves

Using geometry, researchers coax human embryonic stem cells to organize themselvesBy confining colonies of human embryonic stem cells to tiny circular patterns on glass plates, researchers have for the first time coaxed them into organizing themselves just as they would under natural conditions. More »

Tags: , , , ,

Potential Alzheimer’s drug prevents abnormal blood clots in the brain

Potential Alzheimer’s drug prevents abnormal blood clots in the brainThe brains of Alzheimer’s mice treated with the compound RU-505 showed less inflammation and better blood flow than those of untreated mice. The treated mice also performed better on memory tests. More »

Tags: , , , , , ,

Sequencing efforts miss DNA crucial to bacteria’s disease causing power

Sequencing efforts miss DNA crucial to bacteria’s disease causing powerPieces of DNA, including viruses, found outside a microbe’s chromosomes may play a role in disease, but are nearly impossible to identify and sequence using conventional techniques. Researchers at Rockefeller have developed a solution. More »

Tags: , , , , ,

New monkey model for AIDS offers promise for medical research

New monkey model for AIDS offers promise for medical researchRockefeller University researchers announce that they have coaxed a slightly modified form of the HIV-1 virus to not only infect pigtailed macaques but to cause full blown AIDS in the primates, an accomplishment that could accelerate the search for new AIDS treatments or vaccines. More »

To recover consciousness, brain activity passes through newly detected states

To recover consciousness, brain activity passes through newly detected statesResearch shows that recovery from deep anesthesia is not a smooth, linear process but is instead a dynamic journey with specific states of activity the brain must temporarily occupy on the way to full recovery. More »

Tags: , , ,

Research details how developing neurons sense a chemical cue

Netrin-1_Xu_thumb_05302014New structural images help explain how young neurons make the right connections, showing how a signal, Netrin-1, interacts with specific receptors that tell neurons in which direction to reach.
More »

Tags: , , , , , ,

Researchers profile active genes in neurons based on connections

140519_friedman_retrotrap1_thumbA new technique allows researchers to examine gene expression in neurons that send messages to a synapse. A test run examined dopamine neurons that project to the brain region known as the nucleus accumbens.
More »

Tags: , , , , , ,

Searching for drugs in dirt, researchers call on citizen scientists

dirtonscale_thumb_2014 Soil microbes are believed to make a wealth of as-yet undiscovered molecules, including antibiotics. But getting at them isn’t easy. To make these potentially helpful bugs easier to find, researchers want to create maps, and they need help.
More »

Tags: , , , , ,

Stem cell progeny tell their parents when to turn on

Hsu-follicle-vertical-05052014During an infection, the immune system selects B cells that produce antibodies with a high affinity for the pathogen. New research helps explain the details of how these cells are selected and amplified. More »

Tags: , , , ,

Discovery helps explain how B cells adapt to their targets

Gitlin-b-cells-thumb2-05052014During an infection, the immune system selects B cells that produce antibodies with a high affinity for the pathogen. New research helps explain the details of how these cells are selected and amplified. More »

Tags: , , , , ,