Category Archives: Science News
This new tool promises to allow scientists to explore the as-yet-unknown details of how cells unzip the double-stranded DNA molecule and replicate it, a process crucial to life. More »
Researchers at Rockefeller University have determined that the Abdominal-B (Abd-B) gene, previously known as the gene that sculpts the posterior parts of the developing fly, is also important for a complex courtship behavior, at least in the case of female flies. More »
By confining colonies of human embryonic stem cells to tiny circular patterns on glass plates, researchers have for the first time coaxed them into organizing themselves just as they would under natural conditions. More »
The brains of Alzheimer’s mice treated with the compound RU-505 showed less inflammation and better blood flow than those of untreated mice. The treated mice also performed better on memory tests. More »
Pieces of DNA, including viruses, found outside a microbe’s chromosomes may play a role in disease, but are nearly impossible to identify and sequence using conventional techniques. Researchers at Rockefeller have developed a solution. More »
Rockefeller University researchers announce that they have coaxed a slightly modified form of the HIV-1 virus to not only infect pigtailed macaques but to cause full blown AIDS in the primates, an accomplishment that could accelerate the search for new AIDS treatments or vaccines. More »
Research shows that recovery from deep anesthesia is not a smooth, linear process but is instead a dynamic journey with specific states of activity the brain must temporarily occupy on the way to full recovery. More »
New structural images help explain how young neurons make the right connections, showing how a signal, Netrin-1, interacts with specific receptors that tell neurons in which direction to reach.
A new technique allows researchers to examine gene expression in neurons that send messages to a synapse. A test run examined dopamine neurons that project to the brain region known as the nucleus accumbens.
Soil microbes are believed to make a wealth of as-yet undiscovered molecules, including antibiotics. But getting at them isn’t easy. To make these potentially helpful bugs easier to find, researchers want to create maps, and they need help.
During an infection, the immune system selects B cells that produce antibodies with a high affinity for the pathogen. New research helps explain the details of how these cells are selected and amplified. More »
Researchers have found that the fastener proteins that organize cell division can harness the movement around them to do their work. Movement of filaments within the structure responsible for cell division can cause some of these proteins to shuffle along the path of least resistance and into position. More »
With the Human Gene Connectome, an investigator can rank potential disease-causing genes based on a new metric called biological distance. This tool is now available online thanks in part to the work of two high school students. More »
The sodium-potassium pump, a ubiquitous and essential molecule located in the membrane of cells, transports more than just the sodium and potassium that its name would suggest. New research shows these pumps also routinely transport hydrogen ions known as protons. Among other things, the work suggests a new dimension to molecules that underlie processes involved in nerve signaling and muscle contractions. More »
Rockefeller researchers tested the sensitivity of volunteers’ noses and brains, and determined that the human sense of smell is far more refined than previously thought. While individual volunteers’ performance varied, on average people can tell the difference between complex mixtures of odors even when they contain many of the same components. More »
In the race for better treatments and possible cures, rare diseases are often left behind. In a collaboration of researchers at The Rockefeller University, Memorial Sloan Kettering Cancer Center and the New York Genome Center, an unusual mutation has been found that is strongly linked to one such disease: a rare liver cancer that affects teens and young adults. More »
Researchers used a genome editing technique to engineer a mutant version of the Aedes aegypti mosquito, which spreads yellow fever. The mutant was unable to detect carbon dioxide, and studies showed that this hindered its ability to detect a host, even in the presence of other sensory cues like heat and odor. The results can help inform the design of chemical repellents to block host-seeking behavior in both Aedes aegypti and Anopheles gambiae, which spreads malaria. More »