Category Archives: Science News
Although many participants gave high marks to the research teams’ trustworthiness and ability to explain their protocols, the survey also revealed that a sizable minority did not feel completely prepared for the study. The results suggest aspects of the participant experience that researchers may be able to address. More »
Jean-Laurent Casanova, head of the Laboratory of Human Genetics of Infectious Diseases, and colleagues at Necker Medical School in Paris have discovered a genetic deficiency that in rare cases allows the dermatophyte fungus, which causes ringworm, to spread below the skin’s surface and onto the lymph nodes, bones, digestive tract and even the brain. More »
Rockefeller scientists revealed the first genome-wide RNA interference screen of a mouse, using a new technique that essentially treats the surface of living mouse embryos as a petri dish of cells, allowing for in vivo analysis. More »
A collaboration between Elaine Fuch’s Laboratory of Mammalian Cell Biology and Development at Rockefeller University and researchers at Duke University and the University of California, San Francisco, found that blocking a molecule called TRPV4 greatly protects against the painful effects of sunburn. The research could yield a way to combat sunburn and possibly several other causes of pain. More »
A collaboration between researchers in Hermann Steller’s Strang Laboratory of Apoptosis and Cancer Biology and Elaine Fuchs’s Laboratory of Mammalian Cell Biology and Development has revealed a new function for a gene previously shown to prevent stem cells from turning cancerous. The gene, Sept4/ARTS, has now been shown to regulate programmed death in skin stem cells, a finding that may have implications for wound healing, regeneration and cancer. More »
Fisher is a postdoc in James Hudspeth’s Laboratory of Sensory Neuroscience studying the biophysics and neurophysiology of the auditory system. He is one of seven winners of the prize, which is given to faculty and postdocs in the tri-state area. More »
Scientists in Leslie Vosshall’s Laboratory of Neurogenetics and Behavior at Rockefeller used a genetically modified mosquito to show that a specific gene called orco gives the insects a strong preference for humans over other mammals, and that the insect repellant DEET uses this pathway to deter mosquitoes from biting. More »
Researchers at The Rockefeller University and the Howard Hughes Medical Institute have identified the mechanism by which the cell’s protein recycler, the proteasome, ramps up its activity to take care of unwanted and potentially toxic proteins. The finding, which has implications for treating muscle wasting and neurodegeneration, also suggests that small molecule inhibitors of this mechanism may be clinically useful in treating multiple myeloma. More »
An international team of scientists led by Rockefeller University researchers has identified the defective gene responsible for a rare disorder in which children are born without a spleen, which makes them susceptible to life-threatening bacterial infections early in life. The findings may lead to new diagnostic tests and raises new questions about the role of this gene in the body’s protein-making machinery.
Scientists at Rockefeller University and Astex Pharmaceuticals have discovered a new broad range antibiotic that kills a wide range of bacteria, including drug-resistant Staphylococcus (MRSA) bacteria that do not respond to traditional drugs, in mice. The antibiotic, Epimerox, targets weaknesses in bacteria that have long been exploited by viruses that attack them, known as phage.
Scientists in David Allis’s laboratory have shown how a mutated histone protein inhibits an enzyme, which normally keeps cell growth in check, and causes a rare form of pediatric brain cancer called DIPG. Their findings reveal a mechanism for inhibiting enzymes and could lead to the development of pharmaceuticals that mimic the action of these mutant proteins.
Researchers at Rockefeller University, along with colleagues at Necker Hospital for Sick Children and the Pasteur Institute in Paris and Ben-Gurion University in Israel, have generated the full set of distances, routes and degrees of separation between any two human genes, creating a map of gene “shortcuts” that aims to simplify the hunt for disease-causing genes in monogenic diseases. More »
Researchers in Elaine Fuchs’ Laboratory of Mammalian Cell Biology and Development have elucidated how adult stem cells in hair follicles communicate with each other and what keeps them silent for prolonged periods of time. More »
Daniel Kronauer and his colleagues at University of Paris 13 have found that when Cerapachys biroi ants execute their fellow colony-members for laying eggs when they shouldn’t, it’s not because of a fight for reproductive dominance, as some had thought. More »
Researchers led by Rockefeller’s Jesse Ausubel analyzed factors such as global land use and population growth over the last 50 years. Looking at the production index of all crops of the UN’s Food and Agriculture Organization, they found that from 1961 to 2009 land farmed grew by only 12 percent while the index rose about 300 percent.
Rockefeller researchers in Michel Nussenzweig’s Laboratory of Molecular Immunology have found that a newly-discovered class of especially potent antibodies is effective at neutralizing HIV infection in mice for a 60 day period, longer than current antiretroviral drugs which require daily application. The antibodies, which suppressed the virus when used in combination, could one day be given to humans to treat the disease. More »
New research from Rockefeller University has shown that chemicals in the brain — neuropeptides known as vasopressin and oxytocin — play a role in coordinating mating and reproductive behavior in animals ranging from humans to fish to invertebrates. More »
A prestigious Rockefeller University award for exceptional women scientists recognizes a pioneer in the field of RNA biology whose discoveries involved patients with a variety of autoimmune diseases. Steitz will receive the award from National Geographic Explorer in Residence Sylvia Earle at a ceremony in Rockefeller’s Caspary Auditorium on November 29. More »
A team of scientists has shown that, at least in the short term, cholesterol levels did not improve when volunteers with vitamin D deficiency received mega-doses of vitamin D. Although previous evidence suggested there might be a link between vitamin D and heart disease, the clinical results confirm those from a data mining study published in July. More »