Category Archives: Science News

Changes in the vascular system may trigger Alzheimer’s disease

In some people whose cognitive functions are weakened due to Alzheimer’s, the disease can be traced back to changes in the brain’s blood vasculature. Scientists have found that a protein involved in blood clotting and inflammation might offer a potential path to new drugs. More »

Tags: , , , , ,

For biologists studying tiny worms, new technologies make big improvements

For biologists studying tiny worms, new technologies make big improvements Two new technologies are helping scientists understand new aspects of organ and nervous system development in C. elegans. One allows them to image worms developing in a natural environment, while the other makes it possible to track single neurons as the worms grow. More »

Tags: , , , , , ,

Early intervention with new treatment provides durable control of HIV-like virus in monkeys

Early intervention with new treatment provides durable control of HIV-like virus in monkeysResearchers have found that a new approach to HIV treatment can suppress an HIV-like virus for an extended period in monkeys. The therapy employs antibodies and takes advantage of the immune system’s natural defenses. More »

Tags: , , , , , , , ,

Study tests the “three-hit” theory of autism

Study tests the “three-hit” theory of autismCould a genetic predisposition to autism together with early stress have a more detrimental effect on boys than on girls? In experiments with mice, researchers found evidence that three factors—genes, environment, and sex—work together to produce problems with social interaction, a hallmark of autism. More »

A new way to reset gene expression in cancer cells shows promise for leukemia treatment

A protein that often is mutated in leukemia cells could represent a potent drug targetScientists have discovered a potential new target for the treatment of leukemia that potentially could augment the activity of BET inhibitors, drugs currently in clinical trials. These therapies act on histones, DNA’s packaging proteins, to reset gene regulatory programs that go awry in cancer.
More »

Tags: , , , , , , , , , ,

New structural studies reveal workings of a molecular pump that ejects cancer drugs

New structural studies reveal workings of a molecular pump that ejects cancer drugsSometimes cells spit out things we don’t want them to—like medications. Researchers have determined the three-dimensional structure of a tiny pump that expels, among other things, chemotherapy agents. This new knowledge could lead to the design of more effective drugs. More »

Tags: , , , , , , , ,

New research explains why a common bacterium can produce severe illness

New research explains why a common Staphylococcus bacterium can produce severe illnessHow can the same infection result in dramatically different levels of illness in two different people? A new study identifies two conditions—a genetic immunodeficiency and delayed acquired immunity—that explain why a patient developed a life-threatening disease in response to a common strain of bacterium. More »

Tags: , , , ,

Crowdsourcing effort helps researchers predict how a molecule will smell

Crowdsourcing effort helps researchers predict how a molecule will smellWhile it’s possible to anticipate the color of light or the pitch of sound, odor defies prediction. New research has taken an important step toward decoding smell, by linking a scent back to a molecule’s chemistry.
More »

Mouse studies offer new insights about cocaine’s effect on the brain

Newly discovered beetle species named after Rockefeller’s Daniel KronauerResearchers have determined how a specific protein regulates the brain’s response to cocaine. Their findings provide fresh insights into the neurobiology of addiction, and could lead to the development of better interventions and treatments.
More »

Tags: , , , , , , ,

Newly discovered beetle species named after Rockefeller’s Daniel Kronauer

Newly discovered beetle species named after Rockefeller’s Daniel KronauerA former Rockefeller postdoctoral associate has named a new species of beetle Nymphister kronaueri, after his mentor, Daniel Kronauer. Discovered in the Costa Rican rainforest, the beetle anchors itself tightly to backside of nomadic ants, hitchhiking a ride to new nesting sites. More »

Tags: , , , ,

Scientists discover an unexpected influence on dividing stem cells’ fate

Scientists reveal an unexpected influence on dividing stem cells' fateWhen it divides, a stem cell has a choice: produce more stem cells or turn into the specific types of cells that compose skin, muscle, brain, or other tissue. New experiments in skin show this decision can be altered if tiny organs within cells aren’t positioned and divvied up properly. More »

Tags: , , , , , , , ,

Encouraging clinical results for an antibody drug to prevent or treat HIV

Encouraging results for an antibody drug to prevent or treat HIVA drug known as 10-1074, based on a human antibody against HIV, has dramatically reduced virus levels in patients and appeared to prevent infection among those at high risk, according to data from a new clinical trial. More »

Tags: , , , , , , , ,

Atomic-scale view of bacterial proteins offers path to new tuberculosis drugs

New molecular insights are giving scientists ideas for how to combat antibiotic-resistant strains
In studying a cousin of the bacterium that causes tuberculosis, scientists have drawn a molecular map of the target for rifampicin, a common antibiotic. They are now using it in an effort to combat multi-resistant tuberculosis, for which existing treatments don’t work. More »

Tags: , , , , , ,

Study reveals the structure of a protein crucial for DNA replication

Study reveals the structure of a protein crucial for DNA replicationFor life to propagate, the instructions in our DNA must be copied and passed on to future generations. Focusing on the structure of the machinery that executes this process, scientists have revealed that the orientation of the proteins involved is different from what has previously been reported. More »

Tags: , , , , ,

Discovery helps explain why only some people develop life-threatening dengue infections

Discovery helps explain why only some people develop life-threatening dengue infectionsAfter contracting dengue fever once, certain people who encounter the virus again develop much more severe infections. New research identifies an immunological signature that could help identify and better treat these patients. More »

Tags: , , , , , , , ,

Researchers explore how protein production gets distorted in skin cancer

Researchers explore how protein production gets distorted in skin cancerResearchers have shown that a shift in translation, the process by which cells produce proteins from RNA, may promote skin cancer. The discovery could potentially aid the development of new treatments.
More »

Tags: , , , , , , ,

Antibody Combination Puts HIV on the Ropes

Antibody combination puts HIV on the ropesResearchers have shown that a combination of three antibody drugs can completely suppress HIV in infected mice. The antibodies were isolated from a patient whose immune system mounted an unusually effective response against the virus. More »

Tags: , , , , , ,

MacKinnon lab charts the anatomy of three molecular channels

MacKinnon lab charts the anatomy of three molecular channelsBy determining the three-dimensional structures of these molecules down to the level of atoms, the researchers have unlocked key details as to how they function in the body. More »

Tags: , , , , , , , , ,

New research offers clues into how the brain shapes perception to control behavior

New research offers clues into how the brain shapes perception to control behaviorSome of the visual information our brains receive is potentially misleading. New research on fruit flies demonstrates how even a simple brain can filter out such misinformation, hinting at how our own brains might shape how we see the world—and how we react to it. More »

Tags: , , , , , , , ,

Scientists learn how to ramp up microbes’ ability to make memories

Scientists learn how to ramp up microbes’ ability to make memoriesResearchers have identified a mutation that prompts bacterial cells to acquire genetic memories 100 times more frequently than they do naturally. This discovery provides a powerful research tool and could bring scientists one step closer to developing DNA-based data storage devices. More »

Tags: , , , , , , , , , ,