Newswire

Rockefeller hosts British Prime Minister David Cameron

pubaff — Fri, 17 May 2013 21:13:33 +0000

Cameron's May 15 visit to the university, part an effort by the British government to acknowledge the value and investment that U.S. biomedical research has in the UK, also included a tour of President Marc Tessier-Lavigne's neuroscience laboratory and a meeting with Nobel Prize winning neurobiologist Paul Greengard. More »

Jean-Laurent Casanova appointed HHMI investigator

pubaff — Thu, 09 May 2013 06:15:29 +0000

Casanova, whose research established for the first time that a predisposition to infectious diseases in children can be genetically determined, has been named one of 27 new investigators with the Howard Hughes Medical Institute. His appointment brings the total number of Rockefeller scientists supported by HHMI to 16. More »

Lewis Thomas Prize to be awarded to Kay Redfield Jamison

pubaff — Tue, 07 May 2013 18:08:57 +0000

Jamison, a professor of psychiatry at The Johns Hopkins University School of Medicine, has made extensive contributions to the field of psychology and is considered one of the country’s foremost authorities on manic-depressive bipolar illness. She is being honored for her 1993 book Touched with Fire: Manic-Depressive Illness and the Artistic Temperament, which examines the relationship between artistic creativity and mood disorders. More »

Nobel laureate Christian de Duve dies at 95

pubaff — Mon, 06 May 2013 18:36:48 +0000

Christian de Duve was a Nobel Prize winning cell biologist whose research centered on the separation and characterization of the organelles of living cells. de Duve and his colleagues also made significant contributions to the development of techniques and instrumentation for the study of cell biology. More »

In the News

pubaff — Mon, 06 May 2013 18:16:53 +0000

Christian de Duve, 95, dies; Nobel-winning biochemist “[Dr. de Duve] discovered the lysosome, a tiny sack filled with enzymes that functions like a garbage disposal, destroying bacteria or parts of the cell that are old or worn out. His … More »

Cell online: May 1, 2013

pubaff — Wed, 01 May 2013 18:14:53 +0000

Cell online: May 1, 2013 Cyclic [G(2',5')pA(3',5')p] is the metazoan second messenger produced by DNA-activated cyclic GMP-AMP synthase Pu Gao, Manuel Ascano, Yang Wu, Winfried Barchet, Barbara L. Gaffney, Thomas Zillinger, Artem A. Serganov, Yizhou Liu, Roger A. Jones, Gunther … More »

Scientists discover new way protein degradation is regulated

pubaff — Thu, 25 Apr 2013 17:56:49 +0000

Researchers at The Rockefeller University and the Howard Hughes Medical Institute have identified the mechanism by which the cell’s protein recycler, the proteasome, ramps up its activity to take care of unwanted and potentially toxic proteins. The finding, which has implications for treating muscle wasting and neurodegeneration, also suggests that small molecule inhibitors of this mechanism may be clinically useful in treating multiple myeloma. More »

Cell 153: 614-627 (4-25-13)

pubaff — Thu, 25 Apr 2013 17:55:10 +0000

Cell 153: 614-627 Proteasome regulation by ADP-ribosylation Park F. Cho-Park and Hermann Steller

Nature online: April 24, 2013

pubaff — Wed, 24 Apr 2013 17:51:12 +0000

Nature online: April 24, 2013 Random convergence of olfactory inputs in the Drosophila mushroom body Sophie J. C. Caron, Vanessa Ruta, L. F. Abbott and Richard Axel

Marc Tessier-Lavigne and Jeffrey Friedman elected to American Academy of Arts and Sciences

pubaff — Wed, 24 Apr 2013 17:38:17 +0000

Tessier-Lavigne, Rockefeller president and head of the Laboratory of Brain Development, and Jeffrey M. Friedman head of the Laboratory of Molecular Genetics, were elected to the honorary society and independent policy research center along with 198 other leaders in science, art, academia and the civic, corporate and philanthropic arenas. The current membership includes some 250 Nobel laureates and more than 60 Pulitzer Prize winners, and 23 other Rockefeller University faculty members are fellows.

Rockefeller announces 31 percent reduction in carbon emissions

pubaff — Thu, 18 Apr 2013 16:19:09 +0000

Five years after the university committed to reducing its carbon footprint as part of Mayor Michael Bloomberg’s 2030 Carbon Challenge, Rockefeller was one of four participating universities that reached their target ahead of schedule. Bloomberg announced the results today at a press conference held in Rockefeller's philosopher's garden. More »

Scientists discover gene mutation that causes children to be born without spleen

pubaff — Fri, 12 Apr 2013 20:19:47 +0000

An international team of scientists led by Rockefeller University researchers has identified the defective gene responsible for a rare disorder in which children are born without a spleen, which makes them susceptible to life-threatening bacterial infections early in life. The findings may lead to new diagnostic tests and raises new questions about the role of this gene in the body’s protein-making machinery.

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In the News

pubaff — Fri, 12 Apr 2013 00:11:52 +0000

Looking to nature for antibiotic inspirations “Bacteriophages, viruses that infect bacterial cells, employ an arsenal of chemical weapons. Microbiologist Vincent Fischetti of Rockefeller University describes using tricks learned from the phage in developing new antibiotics that may be effective … More »

Science online: April 11, 2013

pubaff — Thu, 11 Apr 2013 17:43:44 +0000

Science online: April 11, 2013 Ribosomal protein SA haploinsufficiency in humans with isolated congenital asplenia Alexandre Bolze, Nizar Mahlaoui, Minji Byun, Bridget Turner, Nikolaus Trede, Steven R. Ellis, Avinash Abhyankar, Yuval Itan, Etienne Patin, Samuel Brebner, Paul Sackstein, Anne Puel, … More »

Scientists use Nature against Nature to develop an antibiotic with reduced resistance

pubaff — Wed, 10 Apr 2013 17:00:37 +0000

Scientists at Rockefeller University and Astex Pharmaceuticals have discovered a new broad range antibiotic that kills a wide range of bacteria, including drug-resistant Staphylococcus (MRSA) bacteria that do not respond to traditional drugs, in mice. The antibiotic, Epimerox, targets weaknesses in bacteria that have long been exploited by viruses that attack them, known as phage.

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Nature 496: 110-113 (4-4-13)

pubaff — Thu, 04 Apr 2013 17:38:37 +0000

Nature 496: 110-113 SIRT6 regulates TNF-α secretion through hydrolysis of long-chain fatty acyl lysine Hong Jiang, Saba Khan, Yi Wang, Guillaume Charron, Bin He, Carlos Sebastian, Jintang Du, Ray Kim, Eva Ge, Raul Mostoslavsky, Howard C. Hang, Quan Hao and … More »

In the News

pubaff — Tue, 02 Apr 2013 16:03:44 +0000

Obama to unveil initiative to map the human brain “A working group at the N.I.H., described by the officials as a ‘dream team,’ and led by Cori Bargmann of Rockefeller University and William Newsome of Stanford University, will be … More »

In the News

pubaff — Mon, 01 Apr 2013 16:06:02 +0000

Good Day New York Book Club interviews Erec Stebbins “Erec Stebbins is an award-winning researcher at Rockefeller University. In his spare time, he has written an absorbing thriller about an FBI agent tracking down home grown terrorists. The book is … More »

Mechanism of mutant histone protein in childhood brain cancer revealed

pubaff — Fri, 29 Mar 2013 20:46:56 +0000

Scientists in David Allis’s laboratory have shown how a mutated histone protein inhibits an enzyme, which normally keeps cell growth in check, and causes a rare form of pediatric brain cancer called DIPG. Their findings reveal a mechanism for inhibiting enzymes and could lead to the development of pharmaceuticals that mimic the action of these mutant proteins.

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Cell 153: 126-138 (3-28-13)

pubaff — Thu, 28 Mar 2013 17:24:35 +0000

Cell 153: 126-138 Somatic mutations of the immunoglobulin framework are generally required for broad and potent HIV-1 neutralization Florian Klein, Ron Diskin, Johannes F. Scheid, Christian Gaebler, Hugo Mouquet, Ivelin S. Georgiev, Marie Pancera, Tongqing Zhou, Reha-Baris Incesu, Brooks Zhongzheng … More »