Search Results for: F. Nina Papavasiliou

Nature Immunology online: May 26, 2013

Nature Immunology online: May 26, 2013 A comprehensive analysis of the effects of the deaminase AID on the transcriptome and methylome of activated B cells Eric L. Fritz, Brad R. Rosenberg, Kenneth Lay, Aleksandra Mihailović, Thomas Tuschl and F. Nina … More »

Proceedings of the National Academy of Sciences USA online: December 31, 2012

Proceedings of the National Academy of Sciences USA online: December 31, 2012 Solubility-based genetic screen identifies RING finger protein 126 as an E3 ligase for activation-induced cytidine deaminase Rebecca K. Delker, Yanjiao Zhou, Alexandros Strikoudis, C. Erec Stebbins and F. … More »

Scientists identify DNA that regulates antibody production

When foreign invaders trip the immune system’s alarm, antibodies need to be specially sculpted to attack them head on. New research now shows that gene segments called enhancers control the reshuffling of antibody genes that makes such a precise and coordinated attack possible. More »

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Parasite breaks its own DNA to avoid detection

The parasite Trypanosoma brucei, which causes African sleeping sickness, is like a thief donning a disguise. Every time the host’s immune cells get close to destroying the parasite, it escapes detection by rearranging its DNA and changing its appearance. Now, researchers at Rockefeller University reveal how the parasite initiates its getaway — by cleaving both strands of its DNA. More »

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Scientists identify a key regulator of DNA mutations

As a general rule, your DNA is not something you want rearranged. But there are exceptions — especially when it comes to fighting infections. Now, two teams of researchers at Rockefeller University independently show how a tiny, recently identified molecule once implicated in cancer can not only help defend against it but also keep invading microbes at bay. More »

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