Search Results for: Michael O'Donnell

Clearing jams in the copy machinery

Bacteria and humans use a number of tools to direct perhaps the most important function in cells — the accurate copying of DNA during cell division. Now, Rockefeller scientists show that one of these proteins, the beta sliding clamp, serves as a toolbelt, from which the correct proteins are retrieved to enable DNA replication in the face of DNA damage. More »

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Researchers create the first model of the DNA ‘replication fork’

Researchers create the first model of the DNA ‘replication fork’This new tool promises to allow scientists to explore the as-yet-unknown details of how cells unzip the double-stranded DNA molecule and replicate it, a process crucial to life. More »

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