Search Results for: Sohail Tavazoie

Cancer biologist and physician Sohail Tavazoie is promoted to associate professor

Cancer biologist and physician Sohail Tavazoie receives promotionTavazoie, who joined Rockefeller in 2009, works to understand how cancer cells become able to escape a tumor and invade other organs, a process known as metastasis. He searches for genes and molecular pathways cancer cells exploit in order to metastasize and, with that knowledge, hopes to develop future treatments to prevent or interfere with the process.
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New Innovator Award goes to cancer researcher Sohail Tavazoie

One of Rockefeller’s newest faculty recruits, Tavazoie aims to identify small pieces of RNA, known as microRNAs, that may signal a high potential for metastasis or that can effectively distinguish between cancers that will be responsive to chemotherapy and those that would be better candidates for alternative and experimental therapies. More »

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In the News – Daily Mail UK – Tavazoie

How spread of breast cancer could be stopped “Professor Sohail Tavazoie, who led the research, said: ‘If we learn more about how this regulation works, we may in the future be able to generate drugs that prevent this protein from … More »

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Four Rockefeller scientists named 2016 HHMI Faculty Scholars

Daniel Kronauer, Luciano Marraffini, Agata Smogorzewska, and Sohail Tavazoie are among 84 researchers nationwide selected as the first HHMI Faculty Scholars. The new Faculty Scholars program, established by the HHMI, the Simons Foundation, and the Bill & Melinda Gates Foundation, supports early-career scientists who have potential to make unique contributions to their fields. More »

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Two Rockefeller postdocs recognized by Blavatnik Regional Awards

Two Rockefeller postdocs recognized by Blavatnik Regional Awards

Hani Goodarzi and Ziv Shulman have been named a winner and a finalist, respectively, by the Blavatnik Regional Awards, which honor outstanding postdoctoral scientists in New York, New Jersey, and Connecticut. Goodarzi is a postdoc in Sohail Tavazoie’s lab; Shulman, a former postdoc in Michel Nussenzweig’s lab, has since established his own lab at the Weizmann Institute of Science in Israel.

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Nora Pencheva wins 2014 Weintraub Graduate Student Award

Pencheva, a graduate fellow in Sohail Tavazoie’s Laboratory of Systems Cancer Biology, is one of 13 recipients of this prestigious award. Her thesis project explores the molecular biology of metastatic melanoma — the most deadly type of skin cancer. More »

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New Rockefeller faculty member studies cancer metastasis

Sohail Tavazoie, a physician-scientist whose research focuses on the molecular basis of cancer metastasis, has been named assistant professor and will join The Rockefeller University as head of the Laboratory of Systems Cancer Biology in January 2009. More »


Sebastian Klinge receives 2016 NIH New Innovator Award

Sebastian KlingeGiven by the NIH, the Director’s New Innovator Award recognizes early-career investigators with five-year grants of up to $1.5 million. The award is designed to encourage recipients to pursue projects that have the potential for unusually high impact. Klinge is one of 48 recipients of the prestigious award this year. More »

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Researchers uncover how “silent” genetic changes drive cancer

New insights into muscular dystrophy point to potential treatment avenuesSmall molecules called tRNA, whose job is to help translate genes into proteins, are not usually considered important for understanding the causes of disease. But a new study shows that fluctuations in some tRNAs may in fact influence the progression of breast cancer. More »

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Research identifies a protein that helps determine the fate of RNA

Research identifies a protein that helps determine the fate of RNARNA can be translated into protein or turned into gene-regulating molecules. A newly discovered “reader” recognizes a chemical instruction tag affixed to RNA, an important step in determining the RNA’s destiny. Because of the processes involved, the research has implications for cells’ normal function and disease. More »

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First Winners of Tri-Institutional Breakout Awards Announced

Six young scientists at Memorial Sloan Kettering Cancer Center, Rockefeller University, and Weill Cornell Medical College have been named the inaugural winners of a new prize for postdoctoral investigators in the life sciences. The Breakout Awards were established by three Tri-Institutional winners of the 2013 Breakthrough Prize in Life Science with additional financial support from the institutions themselves. More »

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Fragments of tRNA suggest a novel mechanism for cancer progression

Fragments of tRNA suggest a novel mechanism for cancer progressionResearchers discover that particular genetic fragments, of a type of RNA known as transfer RNA, or tRNA, appear to be capable of reducing the growth and spread of breast cancer cells. More »

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Chemical tag marks future microRNAs for processing, study shows

Chemical tag marks future microRNAs for processing, study showsNew research reveals how cells sort out the RNA molecules destined to become gene-regulating microRNAs by tagging them. Because microRNAs help control processes throughout the body, this discovery has wide-ranging implications for development, health and disease, including cancer.
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Research implicates metabolic process of the liver in the spread of colorectal cancer

Research implicates metabolic process of the liver in the spread of colorectal cancerBy identifying genes that become activated in cancer cells that successfully metastasize to the liver, researchers at Rockefeller have implicated metabolic processes within the liver as a possible means by which starving transient cancer cells can go on to form deadly new colonies. More »

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Discovery of pro-metastasis protein reveals mysterious link to neurodegeneration

Discovery of pro-metastasis protein reveals mysterious link to neurodegenerationMice injected with metastatic breast cancer cells showed less metastasis when researchers silenced the protein TARBP2 in these cells. TARBP2 appears to promote metastasis in part by blocking suppressor genes, including two linked with neurodegeneration. More »

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Drug is identified that could block the spread of melanoma

Researchers have found a promising new route to slowing or even preventing melanoma cells from spreading within the body. Using a compound that targets a hormone receptor, the team found they could reduce tumors’ recruitment of blood vessels, a process necessary for metastasis. More »

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Neurobiologist Vanessa Ruta receives New Innovator Award to fund research on memory wiring in the brain

Ruta, head of the Laboratory of Neurophysiology and Behavior, will use the New Innovator grant, worth nearly $2.5 million over five years, to fund new technical approaches to studying the fly’s olfactory system, including devising new optical labeling techniques which will allow scientists to trace the circuits that encode a specific olfactory association. More »

Five Rockefeller scientists receive high risk-high reward NIH grants

Two Rockefeller University faculty have been awarded the NIH Director’s Transformative Award and three are being given New Innovator Awards.
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In cancer, molecular signals that recruit blood vessels also trigger metastasis

Cancer cells are most deadly when they’re on the move – able not only to destroy whatever organ they are first formed in, but also to create colonies elsewhere in the body. New research has now shown how a small RNA prevents the recruitment and formation of blood vessels near cancer cells destined to become metastases, a process that must occur in order for them to grow. The scientists say that if drugs could be developed that act on the pathways regulated by this microRNA, they might be able to block the metastatic process and prevent some breast cancers from becoming deadly. More »

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Rockefeller University receives nearly $27 million in ARRA grants

Investigators at The Rockefeller University have so far been awarded 41 federal grants and supplemental awards through the American Recovery and Reinvestment Act of 2009 (ARRA) — the so-called “stimulus” legislation passed by Congress last winter. Ranging in size from about $5,000 to nearly $4.6 million, the grants will fund new and ongoing projects in biomedical and clinical research and training. More »