Search Results for: Titia de Lange
Scientists discover new way protein degradation is regulated
Teresa Davoli wins 2013 Weintraub Graduate Student Award
Davoli, a native of Italy, studied a new mechanism of tetraploidization that is induced by dysfunctional telomeres. The Weintraub Awards recognize quality, originality and significance of thesis research. More »
Cori Bargmann, Titia de Lange win inaugural Breakthrough Prizes worth $3 million
Two Rockefeller University scientists are among 11 winners of the first annual Breakthrough Prize in Life Sciences, an award established by six tech entrepreneurs dedicated to advancing breakthrough research. At $3 million each, the prizes are worth more than twice the amount of the Nobel. They were created to recognize excellence in research aimed at curing intractable diseases and extended human life.
Administered by a new non-profit organization, the Breakthrough Prize in Life Sciences Foundation, the prize is founded by Art Levinson, chairman of the board of Apple and former CEO of Genentech; Sergey Brin, co-founder of Google Inc.; Anne Wojcicki, co-founder of 23andMe; Mark Zuckerberg, founder and CEO of Facebook, and his wife Pricilla Chan; and Yuri Milner, founder of the Russian internet company Mail.ru. More »
Tags: Cori Bargmann, Titia de Lange
Proceedings of the National Academy of Sciences USA online: January 22, 2013
Proceedings of the National Academy of Sciences USA online: January 22, 2013 Role of 53BP1 oligomerization in regulating double-strand break repair Francisca Lottersberger, Anne Bothmer, Davide F. Robbiani, Michel C. Nussenzweig and Titia de Lange
Science online: January 10, 2013
Science online: January 10, 2013 53BP1 regulates DSB repair using Rif1 to control 5′ end resection Michal Zimmermann, Francisca Lottersberger, Sara B. Buonomo, Agnel Sfeir and Titia de Lange
Five Rockefeller scientists receive high risk-high reward NIH grants
Two Rockefeller University faculty have been awarded the NIH Director’s Transformative Award and three are being given New Innovator Awards.
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Pearl Meister Greengard Prize to be awarded to pioneering RNA researcher Joan Steitz
A prestigious Rockefeller University award for exceptional women scientists recognizes a pioneer in the field of RNA biology whose discoveries involved patients with a variety of autoimmune diseases. Steitz will receive the award from National Geographic Explorer in Residence Sylvia Earle at a ceremony in Rockefeller’s Caspary Auditorium on November 29. More »
Starr collaboration illuminates mysterious pathway to immortality in cancer cells
Tags: cancer, Telomeres, Titia de Lange
Cell 150: 39-52 (July 6, 2012)
Cell 150: 39-52 Telomeric 3′ Overhangs Derive from Resection by Exo1 and Apollo and Fill-In by POT1b-Associated CST Peng Wu, Hiroyuki Takai and Titia de Lange
Cancer Cell 21: 765-766 (June 12, 2012)
Cancer Cell 21: 765-766 Telomere-driven tetraploidization occurs in human cells undergoing crisis and promotes transformation of mouse cells Teresa Davoli and Titia de Lange
Science 336: 593-597 (May 4, 2012)
Science 336: 593-597 Removal of shelterin reveals the telomere end-protection problem Agnel Sfeir and Titia de Lange
Titia de Lange to receive Heineken Prize
De Lange is honored for her work on telomeres, the protective DNA sequences located at the tips of chromosomes which play a crucial role in such processes as ageing and cancer.
Johannes Scheid wins 2012 Weintraub Graduate Student Award
Scheid is one of 13 awardees, all advanced graduate students at or near the completion of their studies in the biological sciences and chosen for the quality, originality and significance of their thesis research.
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2011 Pearl Meister Greengard Prize to be awarded to McGill University memory researcher
Brenda Milner, a pioneer in the field of cognitive neuroscience whose discoveries revolutionized the understanding of memory, will be awarded the 2011 Pearl Meister Greengard Prize from The Rockefeller University.
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Titia de Lange receives 2011 Vilcek Prize in Biomedical Science
Rockefeller researcher is honored for her research on mechanisms that help maintain genome stability. More »
Two Rockefeller scientists elected to Institute of Medicine
Rockefeller University scientists Robert B. Darnell, head of the Laboratory of Molecular Neuro-oncology, and Titia de Lange, head of the Laboratory of Cell Biology and Genetics, have been elected to the Institute of Medicine, the health and medicine branch of the National Academy of Sciences. More »
Rockefeller postdoc named finalist for Blavatnik Awards for Young Scientists
Agnel Sfeir, a postdoctoral fellow in Titia de Lange’s Laboratory of Cell Biology and Genetics, has been named a finalist in the fourth annual Blavatnik Awards for Young Scientists competition, which recognizes the contributions of young scientists and engineers in New York, New Jersey and Connecticut. More »
Titia de Lange receives AACR Clowes Award
Titia de Lange is the 50th annual recipient of the American Association of Cancer Research’s award to an individual with outstanding recent accomplishments in basic cancer research. More »
Titia de Lange awarded grant, named American Cancer Society Research Professor
The head of Rockefeller University’s Laboratory of Cell Biology and Genetics has received a $400,000 grant from the American Cancer Society and has been named an American Cancer Society Research Professor. The five-year grant, which is effective January 1, 2010, will fund de Lange’s continuing research on telomeres, the strings of extra DNA that cap and protect the ends of chromosomes through numerous cycles of cell division. More »
Handle with care: Telomeres resemble DNA fragile sites
Although telomeres are fragile, they don’t have to be handled with care. Researchers at Rockefeller University now show that what keeps our fragile telomeres from falling apart is a protein known as TRF1 that ensures the smooth progression of DNA replication to the end of a chromosome. The work not only shows how telomeres help chromosomes protect their vulnerable ends but also reveals how the genome is made more stable by them. More »
Tags: Telomeres, Titia de Lange
