Fernando Nottebohm to receive Sackler Prize

Rockefeller University’s Fernando Nottebohm will receive The Mortimer D. Sackler Prize for Distinguished Achievement in Developmental Psychobiology in recognition of his seminal work in songbirds that has led to the discovery of neuronal replacement. More »

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‘Big picture’ of how interferon-induced genes launch antiviral defenses revealed

A team of researchers, led by scientists from Rockefeller University, for the first time has carried out a comprehensive, systematic evaluation of the antiviral activity of factors induced by interferon. The findings, published online today in the journal Nature, are a first step toward unraveling how these naturally occurring molecules work to inhibit viruses. More »

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Researchers put potent staph killer to the test, hope for new drug treatment

The ever escalating war between evolving bacteria and antibiotics could be taking a promising turn in favor of the humans. Scientists have genetically engineered a powerful killer of one of the most dangerous bacteria, methicillin-resistant Staphylococcus aureus (MRSA). It’s been tested on MRSA in the test tube, on infections in mice and a clinical trial has begun to probe its ability to kill MRSA infected cells from psoriasis lesions in people. Next up, per the recommendation of the FDA, is a test in minipigs. “It’s the start of a new class of drugs,” says the lead researcher, and early signs suggest it’s stronger than anything of its kind currently on the market. More »

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Bruce S. McEwen to receive Scolnick Prize for research on brain hormones

Bruce S. McEwen, a pioneer in understanding how hormones affect the brain, will receive the 2011 Edward M. Scolnick Prize in Neuroscience from the McGovern Institute for Brain Research at MIT. McEwen is being honored for research on how hormones affect the brain’s structure, how they shape responses to stress, how they contribute to sexual differences and how they affect our health and well-being. More »

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Bullying alters brain chemistry, leads to anxiety

Getting kicked around is no fun for anyone, but researchers are finding that it’s not just the body that’s bruised, but the brain, too. New experiments from Rockefeller show that mice that are repeatedly bullied by by dominant males grow unusually anxious around new company, threatening or not. The behavioral change seems to be in part due to a change in gene expression that increases sensitivity to vasopressin, a hormone involved in a variety of social behaviors. More »

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University receives accreditation for its human research protection program

Rockefeller University receives the “gold seal” for human subject protection programs, which recognizes the institution’s commitment to providing strong safeguards on behalf of human research participants.

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Elaine Fuchs awarded 2011 Albany Medical Center Prize

Rockefeller scientist is recognized for her contributions toward realizing the vast potential of stem cells to treat and reverse disease. More »

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Marc Tessier-Lavigne becomes Rockefeller’s tenth president

Marc Tessier-Lavigne, a leading neuroscientist and the former chief scientific officer of Genentech, takes over as president of The Rockefeller University today, replacing Paul Nurse, who has left to become president of the Royal Society in London. More »

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Elaine Fuchs to receive Passano Award

World leader in skin biology and its human genetic disorders is honored for landmark contributions to skin biology and its disorders, including genetic syndromes, stem cells and cancers. More »

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Molecule that spurs cell’s recycling center may help Alzheimer’s patients

A molecule that activates the cell’s natural recycling program may flush away the protein fragments that accumulate and form senile plaques in Alzheimer’s disease. New research suggests that stimulating this activity, either through drugs or natural processes, may improve the quality of life for people with diseases caused by built-up proteins in the brain. More »

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New genetic technique probes the cause of skin cell differentiation in mammals

Most complex genetic experiments have been done in simple model organisms like flies and worms, because they’re easier to work with. But new research at Rockefeller University has applied the technique of RNA interference to probe the DNA of our fellow mammal, the mouse. In the process, the researchers are uncovering a deeper understanding of cell differentiation in early development, and hope to apply the results to cancer research. More »

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Titia de Lange receives 2011 Vilcek Prize in Biomedical Science

Rockefeller researcher is honored for her research on mechanisms that help maintain genome stability. More »

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‘Round-the-clock’ lifestyle could disrupt metabolism, brain and behavior

The modern world twists our ancient and natural sleep cycles with ubiquitous electric lighting, shift-work and the like. Now new research in mice suggests that the disturbance could have a serious impact on the body and brain, from weight gain and cognitive inflexibility to poor impulse control. More »

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Newly discovered deep sea lobster named for Rockefeller’s Jesse Ausubel

A newly discovered deep sea lobster is one of many species identified for the first time through the Census of Marine Life, a decade-long project that sponsored 540 expeditions carried out by 2700 researchers from more than 80 countries. More »

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New research traces evolutionary path of multidrug resistant strep bacteria

In a landmark paper published this week in Science, scientists from Rockefeller University and the Sanger Institute have used full genome sequencing to identify the precise steps in the molecular evolution of Streptococcus pneumoniae. Their research shows the changes the genome of this bacterium has undergone in time and during its massive geographic spread over the globe. More »

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Rockefeller joins Pfizer’s Global Centers For Therapeutic Innovation

A new partnership will mimic a venture capital-funded biotechnology start-up model, whereby Pfizer funds pre-clinical and clinical development programs in return for the opportunity to potentially broaden its pipeline with novel and highly differentiated candidate drugs. More »

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Amy C. Falls appointed chief investment officer and vice president for investments

Amy C. Falls will be The Rockefeller University’s chief investment officer and vice president for investments effective April 4, 2011. Falls will oversee the University’s Office of Investments and manage the institution’s endowment, which has an estimated value of $1.8 billion. More »

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Research shows when stem cell descendants lose their versatility

The precocious progenitors of every cell in the body — stem cells — have commitment issues. They must remain unattached to maintain the versatility they need to respond to injuries, regenerate tissues and do their other jobs. New research defines the point at which a developing lineage of hair follicle stem cells do settle down, however, and commit to their mission to grow new hair. The findings also reflect a new concept in stem cell biology: that the newly specialized cells send signals back to the stem cells from which they originated, regulating their behavior. More »

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Robert B. Darnell and Victor Wilson named 2010 AAAS Fellows

Rockefeller University scientists Robert B. Darnell and Victor Wilson have been awarded the distinction of AAAS Fellow. Election as a fellow is an honor bestowed upon AAAS members by their peers. More »

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Scientists identify protein that drives survival of gastrointestinal tumors

Since the introduction of Gleevec as a treatment for gastrointestinal stromal tumors, survival rates have climbed dramatically and recurrence has fallen by two-thirds. But over time, many patients develop resistance to the drug. Now, scientists at Rockefeller University and Memorial Sloan-Kettering Cancer Center have identified a molecule that acts as a survival factor for gastrointestinal tumors, a finding that may lead to next-generation therapies that can pick up where Gleevec leaves off. More »

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