Researchers watch in 3D as neurons talk to each other in a living mouse brain

Researchers watch in 3D as neurons talk to each other in a living mouse brainWhen the brain is at work, neurons talk rapidly to one another, forming networks. Using a new method based on so-called light sculpting, scientists have recorded the activity in these networks within three-dimensional sections of the brains of mice. More »

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Pioneering drug discovery company Bridge Medicines launched to advance promising early technologies in major academic institutions through human proof of concept

Pioneering drug discovery company bridge medicines launched to advance promising early technologies in major academic institutions through human proof of conceptThe Tri-Institutional Therapeutics Discovery Institute, a partnership between Memorial Sloan Kettering Cancer Center, The Rockefeller University, Weill Cornell Medicine and Takeda, joins with Deerfield Management and Bay City Capital to create an accelerated path to innovative therapies to treat disease.
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Winrich Freiwald wins Columbia University’s 2016 W. Alden Spencer Award

Winrich FreiwaldThe award, given by Columbia University, recognizes outstanding research contributions in neuroscience. Freiwald, who shares the prize with his long-time collaborator Doris Y. Tsao of Caltech, will present an award lecture on November 1 at the Columbia University College of Physicians and Surgeons. More »

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Genomic testing could speed research on skin disease and bring new drugs to patients faster

Mayte Suarez-Farinas and Joel Correa da Rosa in Greenberg BuildingWhen a person suffering from psoriasis starts taking a new therapy, it can currently take months to assess if the drug is working. But according to a recent study, that process could be significantly sped up with genomic testing and analysis. More »

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Study uncovers how cells organize the growth of their structural filaments

Study uncovers how cells organize the growth of their structural filamentsResearchers have described how two proteins work together to guide the assembly of important structural elements known as microtubules within the cell. This discovery helps explain how cells prepare to use these filaments. More »

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A possible explanation for why male mice tolerate stress better than females

A possible explanation for why male mice tolerate stress better than femalesRockefeller scientists have described a molecular mechanism that may explain in part why anxiety levels vary between the sexes. The research team identified a molecule that halts the action of a stress-inducing hormone—but it only does so in male mice. More »

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Sebastian Klinge receives 2016 NIH New Innovator Award

Sebastian KlingeGiven by the NIH, the Director’s New Innovator Award recognizes early-career investigators with five-year grants of up to $1.5 million. The award is designed to encourage recipients to pursue projects that have the potential for unusually high impact. Klinge is one of 48 recipients of the prestigious award this year. More »

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Rockefeller graduate Monica Mugnier wins 2016 NIH Early Independence Award

Monica MugnierA 2016 graduate of Rockefeller’s Ph.D. program, Mugnier is one of 16 junior scientists across the country to receive an Early Independence Award. The award, which is given as a five-year grant of up to $1.25 million, allows exceptional investigators to skip postdoctoral training and move immediately into independent research positions. More »

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Study explains how an intestinal microbe protects against other, more dangerous bacteria

Worm Cross Section ThumbnailWorking in animal models, scientists have found that an enzyme produced by one microbe can shield the gut against attack from other, more harmful bacteria. The findings could potentially inform the design of new probiotics for use against dangerous pathogens like those spreading hospital-acquired infections. More »

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Rockefeller University awarded $27 million NIH grant to fund clinical and translational science in Hospital

The five-year “CTSA” grant will enable clinical work based at The Rockefeller University Hospital. The Clinical and Translational Science Award, given by the NIH, is designed to improve the translational research process and foster innovation in research methods, training, and career development. More »

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Bonnie Bassler to receive the 2016 Pearl Meister Greengard Prize

Bonnie Bassler to receive the 2016 Pearl Meister Greengard PrizeBassler, of Princeton University and the Howard Hughes Medical Institute, is being recognized for discoveries related to a molecular mechanism that allows bacteria to communicate with each other. The prize is intended to honor the extraordinary work of established women scientists and to motivate young women considering careers in the sciences. More »

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New research clarifies how cells take in cholesterol and offers insight on Ebola

New research clarifies how cells take in cholesterol and offers insight on EbolaCholesterol is essential for human health, but getting too much of it can contribute to potentially fatal diseases. New research on the structure of two cholesterol-transporting proteins helps explain how cells use only the amount they need. It also offers new insights into the biology of Ebola. More »

A compound that stops cells from making protein factories could lead to new antifungal drugs

A newly identified compound shows promise for fighting fungal infectionsRibosomes manufacture all the protein cells need, making them an appealing target for researchers seeking to develop new medicines. New research in yeast has identified a compound that prevents the assembly of ribosomes, raising hopes for drug development. More »

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Four Rockefeller scientists named 2016 HHMI Faculty Scholars

Daniel Kronauer, Luciano Marraffini, Agata Smogorzewska, and Sohail Tavazoie are among 84 researchers nationwide selected as the first HHMI Faculty Scholars. The new Faculty Scholars program, established by the HHMI, the Simons Foundation, and the Bill & Melinda Gates Foundation, supports early-career scientists who have potential to make unique contributions to their fields. More »

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Rockefeller neuroscientist Cori Bargmann to lead science work at Chan Zuckerberg Initiative

Cori BargmannBargmann will oversee a multi-billion dollar effort over the coming years to develop and implement a strategy to unlock understanding of the human body down to the cellular level. She will also continue as a tenured professor conducting research at Rockefeller.
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Scientists uncover a clever ranking strategy bacteria use to fight off viruses

Scientists uncover a clever ranking strategy bacteria use to fight off virusesLike humans, bacteria come under attack from viruses—and their immune systems, like ours, are capable of remembering a virus so as to preempt any future invasion. New research explores how the bacterial immune system CRISPR stores and ranks these memories. More »

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Charles M. Rice wins Lasker Award for groundbreaking work on the hepatitis C virus

Charles M. RiceThis year’s Lasker-DeBakey Clinical Medical Research Award honors Charles M. Rice, who developed a system to study the replication of the virus that causes hepatitis C, an advance that has led to safe and powerful new drugs that cure the disease. The award, considered the most coveted American prize in medical science, will be presented on September 23 in New York City. More »

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Researchers find combined effects of two genes responsible for premature skull fusion in infants

Researchers identify mutations responsible for premature skull fusion in infantsA combination of rare and common genetic variants can cause the bones at the top of the head to unite prematurely, resulting in deformities and, in some cases, neurodevelopmental problems. This discovery will help to diagnose the condition and identify families at risk, while advancing the understanding of complex genetic traits. More »

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Richard P. Lifton assumes office as the university’s 11th president

Richard P. Lifton assumes office as the university’s 11th presidentA physician-scientist widely recognized for uncovering the underlying causes of hypertension and other diseases, Lifton takes office on September 1. He replaces Marc Tessier-Lavigne, who left to lead Stanford University. More »

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Four postdocs honored with 2016 Tri-Institutional Breakout Awards

The prize recognizes promising young scientists from Memorial Sloan Kettering Cancer Center, Rockefeller University, and Weill Cornell Medicine. Four postdoctoral investigators have won the awards, which were established last year by three winners of the 2013 Breakthrough Prize in Life Sciences from those institutions’ faculty. More »

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