Glands and Ducts Reveals Roles in Homeostasis and Wound Repair
Herpes in STAT1 deficiency
Scale invariance in the dynamics of spontaneous behavior
Mechanistic basis for low threshold mechanosensitivity in voltage-dependent K+ channels
Tiki1 Is Required for Head Formation via Wnt Cleavage-Oxidation and Inactivation
Apoptotic and antitumor activity of death receptor antibodies require inhibitory Fcγ receptor engagement
Mouse model of endemic Burkitt translocations reveals the long-range boundaries of Ig-mediated oncogene deregulation
Telomere-driven tetraploidization occurs in human cells undergoing crisis and promotes transformation of mouse cells
Dynamics of TGF-β signaling reveal adaptive and pulsatile behaviors reflected in the nuclear localization of transcription factor Smad4
dSarm/Sarm1 Is Required for Activation of an Injury-Induced Axon Death Pathway
Contingency and statistical laws in replicate microbial closed ecosystems
Expression of the zinc finger transcription factor zDC (Zbtb46, Btbd4) defines the classical dendritic cell lineage
Radio-wave heating of iron oxide nanoparticles can regulate plasma glucose in mice
Viral-induced encephalitis initiates distinct and functional CD103+ CD11b+ brain dendritic cell populations within the olfactory bulb
Both prizes recognize Friedman’s discovery of the leptin pathway and its role in regulating body weight. Together the prizes are worth nearly $750,000; Friedman shares both with Douglas Coleman, emeritus scientist at the Jackson Laboratory.
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Jeff Friedman to receive King Faisal and BBVA prizes
Wiley Prize in Biomedical Sciences awarded to Mike Young and colleagues
The researchers are being honored for their discovery of the molecular mechanisms governing circadian rhythm. This is the fourth major award Young and his colleagues have received in the past two years, including the Massry Prize, the Canada Gairdner International Award and the Louisa Gross Horwitz Prize from Columbia University. More »
Ant executions serve a higher purpose, research shows
Daniel Kronauer and his colleagues at University of Paris 13 have found that when Cerapachys biroi ants execute their fellow colony-members for laying eggs when they shouldn’t, it’s not because of a fight for reproductive dominance, as some had thought. More »
Changes in population growth, consumption and farming begin to return former farmlands to nature
Researchers led by Rockefeller’s Jesse Ausubel analyzed factors such as global land use and population growth over the last 50 years. Looking at the production index of all crops of the UN’s Food and Agriculture Organization, they found that from 1961 to 2009 land farmed grew by only 12 percent while the index rose about 300 percent.
New neuroscience textbook will be a free reference for students in developing countries
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Charles M. Rice awarded Dautrebande Prize
Rice, head of the Laboratory of Virology and Infectious Disease at Rockefeller, has been awarded the 100,000 euro prize for his description of the molecular and cellular basis of hepatitis C infection in humans.
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Robert Darnell named president of New York Genome Center
Darnell will direct all aspects of the NYGC, including its scientific and research activities, and the recruitment and development of a world-class scientific team in genomic research and medicine. Founded in 2010, the NYGC will be one of the largest genomics research facilities in North America, integrating sequencing, bioinformatics and data management. More »
Brain displays an intrinsic mechanism for fighting infection
Researchers in the St. Giles Laboratory of Human Genetics of Infectious Diseases have shed light on how a genetic defect leaves some children susceptible to a rare and damaging brain infection and have found evidence of an intrinsic immune mechanism in the brain that fights the viral infection in healthy people. More »
Potent antibodies neutralize HIV and could offer new therapy, study finds
Rockefeller researchers in Michel Nussenzweig’s Laboratory of Molecular Immunology have found that a newly-discovered class of especially potent antibodies is effective at neutralizing HIV infection in mice for a 60 day period, longer than current antiretroviral drugs which require daily application. The antibodies, which suppressed the virus when used in combination, could one day be given to humans to treat the disease. More »
Tags: antibodies, Florian Klein, HIV, Michel C. Nussenzweig
Nicholson Lecture brings vascular biologist to speak at Rockefeller as part of exchange program with Karolinska Institute
Christer Betsholtz will visit the Rockefeller University campus as part of a recently renewed program that supports research exchanges between the university and the Karolinska Institute. Betsholtz studies vascular biology, with a focus on cellular and molecular mechanisms for angiogenesis and vascular permeability. More »
Neurotransmitters linked to mating behavior are shared by mammals and worms
New research from Rockefeller University has shown that chemicals in the brain — neuropeptides known as vasopressin and oxytocin — play a role in coordinating mating and reproductive behavior in animals ranging from humans to fish to invertebrates. More »
Elaine Fuchs awarded distinguished medal from New York Academy of Medicine
Fuchs, head of the Laboratory of Mammalian Cell Biology and Development at Rockefeller University, will be awarded the 2012 Academy Medal for Distinguished Contributions in Biomedical Science for her innovative and imaginative approaches to research in skin biology, its stem cells and its associated human genetic disorders. More »
Rockefeller fellow receives NIH ‘early independence award’ to study immune responses with high throughput sequencing
A 2012 graduate of the Tri-Institutional M.D.-Ph.D. program, Brad Rosenberg is one of 14 early-career investigators across the country to receive an NIH Director’s Early Independence Award, a five-year, $2.1 million grant that will allow him to establish his own research program at Rockefeller. More »
Shai Shaham and Sean Brady receive promotions
Shaham, head of the Laboratory of Developmental Genetics, studies the control of programmed cell death during animal development and the roles of glial cells in nervous system development and function. He has been awarded tenure and promoted to professor. Brady, head of the Laboratory of Genetically Encoded Small Molecules, looks for new genetically encoded small molecules from bacterial sources, chemicals that may play a role in the development of new pharmaceuticals. He has been promoted to associate professor.
Tags: Sean Brady, Shai Shaham
Jeffrey M. Friedman awarded 11th IPSEN Endocrine Regulation Prize
Friedman is being recognized for his groundbreaking discovery of leptin, a hormone that regulates food intake and energy expenditure. His observations provided scientists with a new target for treating obesity and other metabolic diseases.
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Five Rockefeller scientists receive high risk-high reward NIH grants
Two Rockefeller University faculty have been awarded the NIH Director’s Transformative Award and three are being given New Innovator Awards.
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Pearl Meister Greengard Prize to be awarded to pioneering RNA researcher Joan Steitz
A prestigious Rockefeller University award for exceptional women scientists recognizes a pioneer in the field of RNA biology whose discoveries involved patients with a variety of autoimmune diseases. Steitz will receive the award from National Geographic Explorer in Residence Sylvia Earle at a ceremony in Rockefeller’s Caspary Auditorium on November 29. More »
Vitamin D supplements do not improve cholesterol as previous research suggested
A team of scientists has shown that, at least in the short term, cholesterol levels did not improve when volunteers with vitamin D deficiency received mega-doses of vitamin D. Although previous evidence suggested there might be a link between vitamin D and heart disease, the clinical results confirm those from a data mining study published in July. More »
Researchers demonstrate how ‘interfering’ RNA can block bacterial evolution
Experiments in pneumococcal bacteria show how an RNA interference mechanism known as CRISPR can be used to prevent the uptake of genetic material from the environment. Harnessing this mechanism could be a new way to manipulate bacterial evolution in ways that might be medically useful. More »
Tags: bacteria, CRISPR, Luciano Marraffini, RNA interference
Michael W. Young receives Massry Prize
The prize recognizes outstanding contributions to the biomedical sciences and the advancement of health, and Young is being honored for his groundbreaking work on the molecular biology of circadian rhythms. Young’s work spans nearly three decades of research on the biological clocks that regulate our bodies’ patterns of sleep and wakefulness, metabolism and response to disease. More »
Tags: Massry Prize, Michael W. Young
