Scientists in David Allis’s laboratory have shown how a mutated histone protein inhibits an enzyme, which normally keeps cell growth in check, and causes a rare form of pediatric brain cancer called DIPG. Their findings reveal a mechanism for inhibiting enzymes and could lead to the development of pharmaceuticals that mimic the action of these mutant proteins.
Hang, a chemist who works to develop new tools for the study of host-pathogen interactions, has discovered that many proteins involved in host immunity to viruses and bacteria are regulated by fatty acid modifications.
Researchers at Rockefeller University, along with colleagues at Necker Hospital for Sick Children and the Pasteur Institute in Paris and Ben-Gurion University in Israel, have generated the full set of distances, routes and degrees of separation between any two human genes, creating a map of gene “shortcuts” that aims to simplify the hunt for disease-causing genes in monogenic diseases. More »
Pasarow awards, first presented in 1987, honor extraordinary achievement, creativity and distinction in the areas of cancer, cardiovascular disease and neuropsychiatry.
Rockefeller University will host a series of workshops this weekend designed to help scientists and educators prepare for the adoption of new standards for teaching science in elementary and high schools. More »
Davoli, a native of Italy, studied a new mechanism of tetraploidization that is induced by dysfunctional telomeres. The Weintraub Awards recognize quality, originality and significance of thesis research. More »
Ruta, head of the Laboratory of Neurophysiology and Behavior, is being recognized for her promise as a scientific leader and will receive a $50,000 prize to further her research on how neural circuits are modified by experience. More »
Two Rockefeller University scientists are among 11 winners of the first annual Breakthrough Prize in Life Sciences, an award established by six tech entrepreneurs dedicated to advancing breakthrough research. At $3 million each, the prizes are worth more than twice the amount of the Nobel. They were created to recognize excellence in research aimed at curing intractable diseases and extended human life.
Administered by a new non-profit organization, the Breakthrough Prize in Life Sciences Foundation, the prize is founded by Art Levinson, chairman of the board of Apple and former CEO of Genentech; Sergey Brin, co-founder of Google Inc.; Anne Wojcicki, co-founder of 23andMe; Mark Zuckerberg, founder and CEO of Facebook, and his wife Pricilla Chan; and Yuri Milner, founder of the Russian internet company Mail.ru. More »
Entering an Unseen World: A Founding Laboratory and Origins of Modern Cell Biology 1910–1974 tells the story of a Rockefeller laboratory from its humble beginnings as a cancer lab, through the founding of the new science of cell biology, to the ultimate prize for scientific accomplishment. More »
Researchers in Elaine Fuchs’ Laboratory of Mammalian Cell Biology and Development have elucidated how adult stem cells in hair follicles communicate with each other and what keeps them silent for prolonged periods of time. More »
Allis leads one of five cancer research teams that are winners of $5 million in grant awards from The Starr Foundation’s Sixth Starr Cancer Consortium Grant Competition.
Both prizes recognize Friedman’s discovery of the leptin pathway and its role in regulating body weight. Together the prizes are worth nearly $750,000; Friedman shares both with Douglas Coleman, emeritus scientist at the Jackson Laboratory.
The researchers are being honored for their discovery of the molecular mechanisms governing circadian rhythm. This is the fourth major award Young and his colleagues have received in the past two years, including the Massry Prize, the Canada Gairdner International Award and the Louisa Gross Horwitz Prize from Columbia University. More »
Daniel Kronauer and his colleagues at University of Paris 13 have found that when Cerapachys biroi ants execute their fellow colony-members for laying eggs when they shouldn’t, it’s not because of a fight for reproductive dominance, as some had thought. More »
Researchers led by Rockefeller’s Jesse Ausubel analyzed factors such as global land use and population growth over the last 50 years. Looking at the production index of all crops of the UN’s Food and Agriculture Organization, they found that from 1961 to 2009 land farmed grew by only 12 percent while the index rose about 300 percent.
The textbook, conceived and edited by Rockefeller University professor Donald W. Pfaff, is a 3,200 page, five-volume overview of both basic science and clinical issues in modern neuroscience, aimed at premedical, medical and graduate students.
Rice, head of the Laboratory of Virology and Infectious Disease at Rockefeller, has been awarded the 100,000 euro prize for his description of the molecular and cellular basis of hepatitis C infection in humans.
Darnell will direct all aspects of the NYGC, including its scientific and research activities, and the recruitment and development of a world-class scientific team in genomic research and medicine. Founded in 2010, the NYGC will be one of the largest genomics research facilities in North America, integrating sequencing, bioinformatics and data management. More »
Rockefeller researchers in Michel Nussenzweig’s Laboratory of Molecular Immunology have found that a newly-discovered class of especially potent antibodies is effective at neutralizing HIV infection in mice for a 60 day period, longer than current antiretroviral drugs which require daily application. The antibodies, which suppressed the virus when used in combination, could one day be given to humans to treat the disease. More »