Research suggests how mosquitoes evolved an attraction to human scent

Research suggests how mosquitoes evolved an attraction to human scentTo understand the evolutionary basis of the mosquito’s attraction to humans, scientists examined the genes that drive preferences of two different subspecies. Their findings suggest that Aedes aegypti aegypti acquired a love for human body odor, a key step in specializing on people. More »

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C. David Allis wins the 2015 Breakthrough Prize in Life Sciences

C. David Allis wins the 2015 Breakthrough Prize in Life Sciences’Allis is recognized for his foundational research on the unexpected regulation of gene activation by modifications to proteins that package DNA, work with implications for many diseases including cancer. The Breakthrough Prize is worth $3 million, making it the richest prize in the life sciences, roughly double the Nobel Prize. More »

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3D deep-imaging advance likely to drive new biological insights

3D deep-imaging advance likely to drive new biological insights’In a significant technical advance, a team of neuroscientists at The Rockefeller University has devised a fast, inexpensive imaging method for probing the molecular intricacies of large biological samples in three dimensions, an achievement that could have far reaching implications in a wide array of basic biological investigations. More »

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Research resolves contradiction over protein’s role at telomeres

Research resolves contradiction over protein’s role at telomeres To determine the role of a protein found in the protective caps on human chromosomes, researchers engineered the telomeres to lack this protein. Previous studies suggested the altered telomeres would attach to one another, but they did not. More »

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Cori Bargmann awarded 2015 Benjamin Franklin Medal

New technique efficiently turns antibodies into highly tuned ‘nanobodies’Rockefeller University neurobiologist Cori Bargmann will receive the 2015 Benjamin Franklin Medal in Life Sciences for contributions that have led to major discoveries elucidating the relationship between genes, neurons, neural circuits and behavior. The award, announced this week, will be presented in April at The Franklin Institute in Philadelphia. More »

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New technique efficiently turns antibodies into highly tuned ‘nanobodies’

New technique efficiently turns antibodies into highly tuned ‘nanobodies’Antibodies’ tiny cousins have many potential uses, but scientists haven’t been able to take advantage of them. However, a new technique may make nanobodies dramatically more accessible for all kinds of research. More »

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One signal means different things to stem cells versus their progeny

One signal means different things to stem cells versus their progenyWhen researchers shut down hair follicle stem cells’ ability to respond to a protein, the cells began dividing prematurely. Meanwhile, when the same was done to their progeny cells, the fate of these cells shifted. More »

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Single gene links susceptibility to rare infections with predisposition to autoimmune disease

Single gene links susceptibility to rare infections with predisposition to autoimmune diseaseWhen scientists scanned the brains of patients who lack a particular immune protein, they saw calcium deposits linked with certain diseases that occur as a result of harmful and unnecessary inflammation. More »

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Atomic map reveals clues to how cholesterol is made

Atomic map reveals clues to how cholesterol is madeAn enzyme embedded in the cell membrane performs a crucial step in the complex process by which cells produce cholesterol. Researchers have examined the enzyme’s structure to better understand how it works. More »

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Newly discovered brain cells explain a prosocial effect of oxytocin

Newly discovered brain cells explain a prosocial effect of oxytocinWhen activated by the ‘love hormone’ oxytocin, a class of star-shaped neurons in the brain’s cortex encourages female mice to take an interest in males, but only when the females are in heat. More »

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Rockefeller neurobiology lab is awarded first-round BRAIN initiative grant

Rockefeller neurobiology lab is awarded first-round BRAIN initiative grantResearchers are developing a technology that uses radio waves or magnetic fields to turn neurons on or off remotely. This tool may allow them to study the role of neural circuits in behavior. More »

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‘Programmable’ antibiotic harnesses an enzyme to attack drug-resistant microbes

“Programmable” antibiotic harnesses an enzyme to attack drug-resistant microbesBy co-opting a system bacteria normally use to defend themselves, researchers targeted and killed off colonies of the antibiotic resistant Staph cells on mouse skin. The treatment left behind the drug-susceptible microbes. More »

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Rockefeller postdoc Stephen Brohawn named Blavatnik Award regional finalist

Rockefeller postdoc Stephen Brohawn named Blavatnik Award regional finalistBrohawn, a member of Roderick MacKinnon’s Laboratory of Molecular Neurobiology and Biophysics, studies how proteins called mechanosensitive ion channels sense mechanical forces. He is one of nine finalists from the New York region. More »

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Stanford’s Lucy Shapiro to receive 2014 Pearl Meister Greengard Prize

Stanford's Lucy Shapiro to receive 2014 Pearl Meister Greengard Prize The Rockefeller University has announced that Lucy Shapiro, professor of developmental biology at Stanford University School of Medicine, will receive the 2014 Pearl Meister Greengard Prize. The annual award, which celebrates the achievements of outstanding women in science, will be presented to Shapiro on the Rockefeller campus November 11. More »

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New technique reveals a role for histones in cell division

New technique reveals a role for histones in cell divisionResearchers have found that key aspects of cell division, such as the formation of the support structure for the envelope that surrounds the nucleus, depend on the presence of DNA-organizing proteins known as histones. More »

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Imaging studies open a window on how effective antibodies are formed

Imaging studies open a window on how effective antibodies are formedBy imaging the immune response, researchers have observed how two types of immune cells interact with one another during a critical period following infection in order to prepare the best antibodies and establish long-lasting protection. More »

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Hironori Funabiki promoted to professor

Funabiki’s research has pointed to a role for DNA-packaging proteins known as histones in the formation of structures involved in cell division, with implications for understanding and treating disease. More »

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Research hints at why stress is more devastating for some

Research hints at why stress is more devastating for someSome bounce back from stress, while others struggle with it, even developing anxiety and depression as a result. In experiments with mice, researchers have revealed the molecular origins of this so-called stress gap.
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Discovery reveals how bacteria distinguish harmful versus helpful viruses

Discovery reveals how bacteria distinguish harmful versus helpful virusesViruses can kill bacteria, or viruses can help the microbes by lending them potentially useful genes. New research shows Staph bacteria have an immune system capable of distinguishing dangerous invaders from potentially beneficial ones. More »

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Research explains how cellular guardians of the gut develop

Research explains how cellular guardians of the intestine developA specialized class of immune cell inhabits the thin layer of tissue that lines the intestine. New experiments reveal how these cells arise, sometimes from other mature immune cells. More »

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