Mutant mosquitoes lose their appetite for humans

Scientists in Leslie Vosshall’s Laboratory of Neurogenetics and Behavior at Rockefeller used a genetically modified mosquito to show that a specific gene called orco gives the insects a strong preference for humans over other mammals, and that the insect repellant DEET uses this pathway to deter mosquitoes from biting. More »

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Mike Young to receive Shaw Prize

Young and two colleagues will be awarded the 2013 Shaw Prize in Life Science and Medicine, worth $1 million. Established in 2002, the Shaw Prize honors individuals who have achieved breakthroughs in academic and scientific research or applications and whose work has resulted in a positive and profound impact on humanity. More »

Rockefeller hosts British Prime Minister David Cameron

Cameron’s May 15 visit to the university, part an effort by the British government to acknowledge the value and investment that U.S. biomedical research has in the UK, also included a tour of President Marc Tessier-Lavigne’s neuroscience laboratory and a meeting with Nobel Prize winning neurobiologist Paul Greengard. More »

Jean-Laurent Casanova appointed HHMI investigator

Casanova, whose research established for the first time that a predisposition to infectious diseases in children can be genetically determined, has been named one of 27 new investigators with the Howard Hughes Medical Institute. His appointment brings the total number of Rockefeller scientists supported by HHMI to 16. More »

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Lewis Thomas Prize to be awarded to Kay Redfield Jamison

Jamison, a professor of psychiatry at The Johns Hopkins University School of Medicine, has made extensive contributions to the field of psychology and is considered one of the country’s foremost authorities on manic-depressive bipolar illness. She is being honored for her 1993 book Touched with Fire: Manic-Depressive Illness and the Artistic Temperament, which examines the relationship between artistic creativity and mood disorders.
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Nobel laureate Christian de Duve dies at 95

Christian de Duve was a Nobel Prize winning cell biologist whose research centered on the separation and characterization of the organelles of living cells. de Duve and his colleagues also made significant contributions to the development of techniques and instrumentation for the study of cell biology. More »

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Scientists discover new way protein degradation is regulated

Researchers at The Rockefeller University and the Howard Hughes Medical Institute have identified the mechanism by which the cell’s protein recycler, the proteasome, ramps up its activity to take care of unwanted and potentially toxic proteins. The finding, which has implications for treating muscle wasting and neurodegeneration, also suggests that small molecule inhibitors of this mechanism may be clinically useful in treating multiple myeloma. More »

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Marc Tessier-Lavigne and Jeffrey Friedman elected to American Academy of Arts and Sciences

Tessier-Lavigne, Rockefeller president and head of the Laboratory of Brain Development, and Jeffrey M. Friedman head of the Laboratory of Molecular Genetics, were elected to the honorary society and independent policy research center along with 198 other leaders in science, art, academia and the civic, corporate and philanthropic arenas. The current membership includes some 250 Nobel laureates and more than 60 Pulitzer Prize winners, and 23 other Rockefeller University faculty members are fellows.

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Rockefeller announces 31 percent reduction in carbon emissions

Five years after the university committed to reducing its carbon footprint as part of Mayor Michael Bloomberg’s 2030 Carbon Challenge, Rockefeller was one of four participating universities that reached their target ahead of schedule. Bloomberg announced the results today at a press conference held in Rockefeller’s philosopher’s garden. More »

Scientists discover gene mutation that causes children to be born without spleen


An international team of scientists led by Rockefeller University researchers has identified the defective gene responsible for a rare disorder in which children are born without a spleen, which makes them susceptible to life-threatening bacterial infections early in life. The findings may lead to new diagnostic tests and raises new questions about the role of this gene in the body’s protein-making machinery.

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Scientists use Nature against Nature to develop an antibiotic with reduced resistance

Scientists at Rockefeller University and Astex Pharmaceuticals have discovered a new broad range antibiotic that kills a wide range of bacteria, including drug-resistant Staphylococcus (MRSA) bacteria that do not respond to traditional drugs, in mice. The antibiotic, Epimerox, targets weaknesses in bacteria that have long been exploited by viruses that attack them, known as phage.

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Mechanism of mutant histone protein in childhood brain cancer revealed

Scientists in David Allis’s laboratory have shown how a mutated histone protein inhibits an enzyme, which normally keeps cell growth in check, and causes a rare form of pediatric brain cancer called DIPG. Their findings reveal a mechanism for inhibiting enzymes and could lead to the development of pharmaceuticals that mimic the action of these mutant proteins.

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Howard Hang promoted to associate professor

Hang, a chemist who works to develop new tools for the study of host-pathogen interactions, has discovered that many proteins involved in host immunity to viruses and bacteria are regulated by fatty acid modifications.

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Researchers create map of “shortcuts” between all human genes

Researchers at Rockefeller University, along with colleagues at Necker Hospital for Sick Children and the Pasteur Institute in Paris and Ben-Gurion University in Israel, have generated the full set of distances, routes and degrees of separation between any two human genes, creating a map of gene “shortcuts” that aims to simplify the hunt for disease-causing genes in monogenic diseases. More »

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Elaine Fuchs to receive Pasarow Award

Pasarow awards, first presented in 1987, honor extraordinary achievement, creativity and distinction in the areas of cancer, cardiovascular disease and neuropsychiatry.

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Rockefeller University hosts workshop on Next Generation Science Standards

Rockefeller University will host a series of workshops this weekend designed to help scientists and educators prepare for the adoption of new standards for teaching science in elementary and high schools. More »

Teresa Davoli wins 2013 Weintraub Graduate Student Award

Davoli, a native of Italy, studied a new mechanism of tetraploidization that is induced by dysfunctional telomeres. The Weintraub Awards recognize quality, originality and significance of thesis research. More »

Vanessa Ruta awarded Sloan Research Fellowship

Ruta, head of the Laboratory of Neurophysiology and Behavior, is being recognized for her promise as a scientific leader and will receive a $50,000 prize to further her research on how neural circuits are modified by experience. More »

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Cori Bargmann, Titia de Lange win inaugural Breakthrough Prizes worth $3 million

Two Rockefeller University scientists are among 11 winners of the first annual Breakthrough Prize in Life Sciences, an award established by six tech entrepreneurs dedicated to advancing breakthrough research. At $3 million each, the prizes are worth more than twice the amount of the Nobel. They were created to recognize excellence in research aimed at curing intractable diseases and extended human life.

Administered by a new non-profit organization, the Breakthrough Prize in Life Sciences Foundation, the prize is founded by Art Levinson, chairman of the board of Apple and former CEO of Genentech; Sergey Brin, co-founder of Google Inc.; Anne Wojcicki, co-founder of 23andMe; Mark Zuckerberg, founder and CEO of Facebook, and his wife Pricilla Chan; and Yuri Milner, founder of the Russian internet company Mail.ru. More »

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New book explores history of cell biology at Rockefeller

Entering an Unseen World: A Founding Laboratory and Origins of Modern Cell Biology 1910–1974 tells the story of a Rockefeller laboratory from its humble beginnings as a cancer lab, through the founding of the new science of cell biology, to the ultimate prize for scientific accomplishment. More »