Alipasha Vaziri, who was appointed a tenure-track associate professor in September, seeks to capture and manipulate interactions among neurons within the living brain. He uses his background in physics to develop innovative ways of recording neural activity quickly and across large areas, all at single-cell resolution. More »
Hani Goodarzi and Ziv Shulman have been named a winner and a finalist, respectively, by the Blavatnik Regional Awards, which honor outstanding postdoctoral scientists in New York, New Jersey, and Connecticut. Goodarzi is a postdoc in Sohail Tavazoie’s lab; Shulman, a former postdoc in Michel Nussenzweig’s lab, has since established his own lab at the Weizmann Institute of Science in Israel.
The channel, Slo2.2, helps restore neurons’ internal electrical state, and so prevents them from firing at too high a frequency for too long, which has the potential to damage the cells. With the new information about Slo2.2’s configuration, researchers can better understand how it accomplishes this. More »
The most common lab animals, rats and mice, can’t tell scientists much about speech disorders. However, a new study shows how songbirds, specifically zebra finches, may be able to aid research on neurodegenerative disorders that affect speech and vocalization. More »
Scientists have gained new insight into the formation of the spindle, which is the molecular machine that divides up genetic material prior to cell division. Their work focuses on the motor protein, kinesin-5, which helps to organize the spindle’s filaments. More »
The Kavli Foundation and The Rockefeller University today announced the formation of the Kavli Neural Systems Institute (Kavli NSI) at Rockefeller, funded by a $20 million endowment supported equally by Kavli and Rockefeller. The Institute will become part of a network of seven Kavli Institutes carrying out fundamental research in neuroscience, and a broader network of 20 Kavli Institutes dedicated to astrophysics, nanoscience, neuroscience, and theoretical physics. More »
The experimental drugs target brain cells’ ability to respond to the chemical messenger glutamate, however, it has been unclear how they work. The recent discovery of a molecular amplification system helps explain how the drugs alter signaling in particular neurons to achieve an antidepressant effect. More »
Hobbs, of the University of Texas Southwestern Medical Center and the Howard Hughes Medical Institute, is being recognized for her work on the genetic determinants of plasma lipoprotein levels and risk for cardiovascular disease. The prize is intended to honor the extraordinary work of established women scientists and to motivate young women considering careers in the sciences. More »
Three nurses at New York state universities have been selected as recipients of the awards, which The Rockefeller University gives annually to support nurses while they pursue independent research. This year’s winners will study sleep disruption associated with asthma in women, the relationship between mothers’ self-perceptions and children’s diet, and how self-perception as a drinker affects smoking. More »
The nuclear pore complex, a gate into and out of the nucleus, is capable of an impressive feat: allowing large molecules to pass through, both selectively and quickly. Researchers have now identified the molecular mechanism that makes this possible. More »
A newly described neural circuit in the brain of C. elegans derives precise and simple information from the smell of food, nudging the animal in the direction of the food source. This discovery shows the worm brain may be more sophisticated in processing sensory information than previously realized. More »
The Golden Goose Award, which honors seemingly obscure federally funded research that has led to major breakthroughs, recognizes Cohen’s development of a map of human population by geographic altitude and Wiesel’s experiments showing cats dots or lights projected on a screen. Cohen’s project has had many applications in fields ranging from microchip manufacturing to human disease, while Wiesel’s discoveries led to a better understanding of the visual system, as well as improved treatment of childhood cataracts.
Scientists have identified a new component of the molecular machinery a cell uses to repair damaged DNA. The discovery adds important knowledge about a fundamental life process that protects from diseases such as cancer. More »
RNA can be translated into protein or turned into gene-regulating molecules. A newly discovered “reader” recognizes a chemical instruction tag affixed to RNA, an important step in determining the RNA’s destiny. Because of the processes involved, the research has implications for cells’ normal function and disease. More »
New research shows that a family of experimental cancer drugs can induce neurological changes in mice. The findings underscore the need for more research to determine whether these compounds can enter the brain, where they potentially might cause side effects such as memory loss. More »
In devising a method to readily grow hepatitis C in the laboratory, scientists might have overcome a major hurdle for basic research into the virus and the disease it causes.
Researchers have identified within neurons a series of molecular interactions — known as a pathway — that can dampen the production of the Alzheimer’s protein amyloid-β. These results suggest a new route in the search for therapies for this degenerative disease. More »
Marraffini, who studies the adaptive immune systems, known as CRISPR-Cas systems, found in some bacteria and used in genome editing, has won the Earl and Thressa Stadtman Scholar Award. Meanwhile, Robert Roeder, who investigates the mechanisms that regulate transcription, the process by which genes are copied into RNA, is the recipient of the Herbert Tabor Research Award.
A new study explains how taste and smell signals travel from a male fruit fly’s sense organs and into his higher brain areas as he assesses a potential mating partner. The research may provide important clues about how our brains integrate different sense perceptions to make decisions. More »