Rockefeller fellow receives NIH ‘early independence award’ to study immune responses with high throughput sequencing

A 2012 graduate of the Tri-Institutional M.D.-Ph.D. program, Brad Rosenberg is one of 14 early-career investigators across the country to receive an NIH Director’s Early Independence Award, a five-year, $2.1 million grant that will allow him to establish his own research program at Rockefeller. More »

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Shai Shaham and Sean Brady receive promotions

Shaham, head of the Laboratory of Developmental Genetics, studies the control of programmed cell death during animal development and the roles of glial cells in nervous system development and function. He has been awarded tenure and promoted to professor. Brady, head of the Laboratory of Genetically Encoded Small Molecules, looks for new genetically encoded small molecules from bacterial sources, chemicals that may play a role in the development of new pharmaceuticals. He has been promoted to associate professor.

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Jeffrey M. Friedman awarded 11th IPSEN Endocrine Regulation Prize

Friedman is being recognized for his groundbreaking discovery of leptin, a hormone that regulates food intake and energy expenditure. His observations provided scientists with a new target for treating obesity and other metabolic diseases.
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Five Rockefeller scientists receive high risk-high reward NIH grants

Two Rockefeller University faculty have been awarded the NIH Director’s Transformative Award and three are being given New Innovator Awards.
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Pearl Meister Greengard Prize to be awarded to pioneering RNA researcher Joan Steitz

A prestigious Rockefeller University award for exceptional women scientists recognizes a pioneer in the field of RNA biology whose discoveries involved patients with a variety of autoimmune diseases. Steitz will receive the award from National Geographic Explorer in Residence Sylvia Earle at a ceremony in Rockefeller’s Caspary Auditorium on November 29. More »

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Vitamin D supplements do not improve cholesterol as previous research suggested

A team of scientists has shown that, at least in the short term, cholesterol levels did not improve when volunteers with vitamin D deficiency received mega-doses of vitamin D. Although previous evidence suggested there might be a link between vitamin D and heart disease, the clinical results confirm those from a data mining study published in July. More »

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Researchers demonstrate how ‘interfering’ RNA can block bacterial evolution

Experiments in pneumococcal bacteria show how an RNA interference mechanism known as CRISPR can be used to prevent the uptake of genetic material from the environment. Harnessing this mechanism could be a new way to manipulate bacterial evolution in ways that might be medically useful. More »

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Michael W. Young receives Massry Prize

The prize recognizes outstanding contributions to the biomedical sciences and the advancement of health, and Young is being honored for his groundbreaking work on the molecular biology of circadian rhythms. Young’s work spans nearly three decades of research on the biological clocks that regulate our bodies’ patterns of sleep and wakefulness, metabolism and response to disease. More »

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Protein proves vital in immune response to bacteria

Research led by Rockefeller University scientists found that a protein once thought to be mainly involved in antiviral immunity is instead vital to fighting a type of bacteria that cause diseases such as tuberculosis and leprosy.
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Jean-Laurent Casanova to receive 2012 Milstein Award

The award is bestowed upon a leading biomedical research scientist who has made outstanding contributions to interferon and cytokine research, either in a basic or applied field. Casanova’s studies have important clinical implications, as they provide a rationale for developing new therapeutic approaches based on an understanding of the host component of infectious diseases. More »

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Collaboration finds kidney disease tied to DNA damage

A research collaboration involving Rockefeller University and more than two dozen other institutions found that patients who had a specific kind of kidney disease — called karyomegalic interstitial nephritis — were likely to also have a mutation on FAN1, a gene that is involved in fixing DNA damage. More »

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Starr collaboration illuminates mysterious pathway to immortality in cancer cells

A detailed analysis of a large panel of so-called ALT cell lines shows that they frequently undergo chromosomal changes and are impaired in their ability to detect and repair damage in their DNA. The work suggests a mechanism by which 10 to 15 percent of human cancers develop. More »

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Jeffrey Ravetch wins 2012 Sanofi – Institut Pasteur Award

The award recognizes researchers for their past or ongoing studies advancing understanding of the life sciences, and Ravetch is being recognized for discovering mechanisms by which antibodies carry out their diverse biological functions. He is one of four scientists to be honored for research projects in tropical and neglected diseases, innovative vaccines, new approaches to drug resistance and therapeutic approaches to senescence. More »

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Sweat glands grown from newly identified stem cells

A team of researchers led by scientists at Rockefeller University have shown how sweat glands develop and how their cells respond to injury. Their research also identifies the stem cells within the sweat glands and sweat ducts and enables scientists to begin to explore the cells’ potential for making tissues for the first time. More »

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Rockefeller’s 54th convocation awards Ph.D.s to 40 graduating students

Each doctoral candidate will be presented for the degree by his or her mentor, a tradition dating back to the university’s first commencement ceremony in 1959. Additionally, two esteemed researchers will receive honorary doctor of science degrees: James E. Darnell Jr. of Rockefeller University and Joan A. Steitz of Yale University. More »

Vanessa Ruta named Pew Scholar in the Biomedical Sciences

Vanessa Ruta, head of the Laboratory of Neurophysiology and Behavior, has been chosen as a Pew Scholar in the Biomedical Sciences by The Pew Charitable Trusts. She is among twenty-two early-career researchers who are being honored for showing outstanding promise in science relevant to the advancement of human health. More »

Cornelia Bargmann receives Kavli Prize in Neuroscience

Bargmann is among the first women scientists to receive the prize, which is awarded biennially for outstanding achievement in advancing our knowledge and understanding of the brain and nervous system.

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Rockefeller scientists pioneer new method to determine mechanisms of drug action

Sarah Wacker, Tarun Kapoor and their colleagues have hit on a new method for determining a drug’s molecular target that takes the guesswork out of the equation. The approach makes use of RNA sequencing and advances in data processing technologies to examine all of the differences between a drug-resistant cell and a normal cell and pinpoint the change most likely to cause resistance, which may suggest the drug’s target. More »

Two Rockefeller postdocs win Blavatnik Awards

Two Rockefeller University postdoctoral fellows have been named winners in the 2012 Blavatnik Awards for Young Scientists competition from The New York Academy of Sciences. Andrey Feklistov, from Seth Darst’s Laboratory of Molecular Biophysics, and Nicholas Stavropoulos, from Michael Young’s Laboratory of Genetics, are among 9 winners and 2 finalists. The awards are given to researchers under the age of 42 who demonstrate highly innovative, impactful and interdisciplinary accomplishments in the life sciences, physical sciences, mathematics and engineering. More »

Rockefeller hosts first Leon Levy Neuroscience Fellows Symposium

The first Leon Levy Neuroscience Fellows Symposium will be held at Rockefeller University on Wednesday, May 16. Levy Fellows from Rockefeller, Columbia and New York universities, Memorial Sloan-Kettering Cancer Center and Weill Cornell Medical College will discuss their latest neuroscience research with current Leon Levy Fellows as well as their mentors, former fellows and principal investigators involved with the fellowship program. More »

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