Glands and Ducts Reveals Roles in Homeostasis and Wound Repair
Herpes in STAT1 deficiency
Scale invariance in the dynamics of spontaneous behavior
Mechanistic basis for low threshold mechanosensitivity in voltage-dependent K+ channels
Tiki1 Is Required for Head Formation via Wnt Cleavage-Oxidation and Inactivation
Apoptotic and antitumor activity of death receptor antibodies require inhibitory Fcγ receptor engagement
Mouse model of endemic Burkitt translocations reveals the long-range boundaries of Ig-mediated oncogene deregulation
Telomere-driven tetraploidization occurs in human cells undergoing crisis and promotes transformation of mouse cells
Dynamics of TGF-β signaling reveal adaptive and pulsatile behaviors reflected in the nuclear localization of transcription factor Smad4
dSarm/Sarm1 Is Required for Activation of an Injury-Induced Axon Death Pathway
Contingency and statistical laws in replicate microbial closed ecosystems
Expression of the zinc finger transcription factor zDC (Zbtb46, Btbd4) defines the classical dendritic cell lineage
Radio-wave heating of iron oxide nanoparticles can regulate plasma glucose in mice
Viral-induced encephalitis initiates distinct and functional CD103+ CD11b+ brain dendritic cell populations within the olfactory bulb
Rockefeller University receives the “gold seal” for human subject protection programs, which recognizes the institution’s commitment to providing strong safeguards on behalf of human research participants.
University receives accreditation for its human research protection program
Elaine Fuchs awarded 2011 Albany Medical Center Prize
Rockefeller scientist is recognized for her contributions toward realizing the vast potential of stem cells to treat and reverse disease. More »
Marc Tessier-Lavigne becomes Rockefeller’s tenth president
Marc Tessier-Lavigne, a leading neuroscientist and the former chief scientific officer of Genentech, takes over as president of The Rockefeller University today, replacing Paul Nurse, who has left to become president of the Royal Society in London. More »
Elaine Fuchs to receive Passano Award
World leader in skin biology and its human genetic disorders is honored for landmark contributions to skin biology and its disorders, including genetic syndromes, stem cells and cancers. More »
Tags: Elaine Fuchs, Passano Award, stem cells
Molecule that spurs cell’s recycling center may help Alzheimer’s patients
A molecule that activates the cell’s natural recycling program may flush away the protein fragments that accumulate and form senile plaques in Alzheimer’s disease. New research suggests that stimulating this activity, either through drugs or natural processes, may improve the quality of life for people with diseases caused by built-up proteins in the brain. More »
New genetic technique probes the cause of skin cell differentiation in mammals
Most complex genetic experiments have been done in simple model organisms like flies and worms, because they’re easier to work with. But new research at Rockefeller University has applied the technique of RNA interference to probe the DNA of our fellow mammal, the mouse. In the process, the researchers are uncovering a deeper understanding of cell differentiation in early development, and hope to apply the results to cancer research. More »
Titia de Lange receives 2011 Vilcek Prize in Biomedical Science
Rockefeller researcher is honored for her research on mechanisms that help maintain genome stability. More »
‘Round-the-clock’ lifestyle could disrupt metabolism, brain and behavior
The modern world twists our ancient and natural sleep cycles with ubiquitous electric lighting, shift-work and the like. Now new research in mice suggests that the disturbance could have a serious impact on the body and brain, from weight gain and cognitive inflexibility to poor impulse control. More »
Newly discovered deep sea lobster named for Rockefeller’s Jesse Ausubel
A newly discovered deep sea lobster is one of many species identified for the first time through the Census of Marine Life, a decade-long project that sponsored 540 expeditions carried out by 2700 researchers from more than 80 countries. More »
Tags: Dinochelus ausubeli, Jesse Ausubel
New research traces evolutionary path of multidrug resistant strep bacteria
In a landmark paper published this week in Science, scientists from Rockefeller University and the Sanger Institute have used full genome sequencing to identify the precise steps in the molecular evolution of Streptococcus pneumoniae. Their research shows the changes the genome of this bacterium has undergone in time and during its massive geographic spread over the globe. More »
Amy C. Falls appointed chief investment officer and vice president for investments
Amy C. Falls will be The Rockefeller University’s chief investment officer and vice president for investments effective April 4, 2011. Falls will oversee the University’s Office of Investments and manage the institution’s endowment, which has an estimated value of $1.8 billion. More »
Research shows when stem cell descendants lose their versatility
The precocious progenitors of every cell in the body — stem cells — have commitment issues. They must remain unattached to maintain the versatility they need to respond to injuries, regenerate tissues and do their other jobs. New research defines the point at which a developing lineage of hair follicle stem cells do settle down, however, and commit to their mission to grow new hair. The findings also reflect a new concept in stem cell biology: that the newly specialized cells send signals back to the stem cells from which they originated, regulating their behavior. More »
Tags: Elaine Fuchs, stem cells, stemness
Robert B. Darnell and Victor Wilson named 2010 AAAS Fellows
Rockefeller University scientists Robert B. Darnell and Victor Wilson have been awarded the distinction of AAAS Fellow. Election as a fellow is an honor bestowed upon AAAS members by their peers. More »
Scientists identify protein that drives survival of gastrointestinal tumors
Since the introduction of Gleevec as a treatment for gastrointestinal stromal tumors, survival rates have climbed dramatically and recurrence has fallen by two-thirds. But over time, many patients develop resistance to the drug. Now, scientists at Rockefeller University and Memorial Sloan-Kettering Cancer Center have identified a molecule that acts as a survival factor for gastrointestinal tumors, a finding that may lead to next-generation therapies that can pick up where Gleevec leaves off. More »
Studies describe key role for a protein in cell division
New research shows how one protein, PRC1, acts in the penultimate stage of cell division to help form the architectural structures, called central spindles, needed before the cell can split in two. More »
Therapy for fearsome brain disease could target blood
Alzheimer’s disease isn’t just about twisted brain cells, but also the blood vessels that feed those neurons. Previous research at Rockefeller University showed that the most common element of telltale plaque deposits in Alzheimer’s brains leads to the formation of tougher blood clots, which could choke off oxygen flow to neurons. The new research shows how these clots are formed, suggesting a target for a drug that might prevent them. More »
Paleovirology expanded: New virus fragments found in animal genomes
New research now points the way to a record of viruses that have insinuated themselves into the genomes of insects and animals, providing clues about their evolutionary history. The findings could enable scientists to learn from genetic “fossils” of viruses in much the same way that they do from retroviruses, which unlike regular viruses, use their host’s genetic machinery to reproduce. More »
2010 Pearl Meister Greengard Prize goes to two pioneers of cancer genetics
Janet Davison Rowley and Mary-Claire King, pioneering cancer geneticists, are the recipients of the 2010 Pearl Meister Greengard Prize awarded by The Rockefeller University. Established by Nobel Prize winner Paul Greengard and his wife, sculptor Ursula von Rydingsvard, the prize honors women who have made extraordinary contributions to biomedical science, a group that historically has not received appropriate recognition and acclaim. More »
New Rockefeller University lab building opens
The Collaborative Research Center, a 125,000 square foot, $500 million building designed specifically to help foster scientific collaboration and encourage interactions between scientists, has opened on Rockefeller’s campus. More »
