Tag Archives: David Allis

Scientists find evidence that cancer can arise from changes in the proteins that package DNA

Scientists find evidence that cancer can arise from changes in the proteins that package DNAMutations in histones, the proteins that shield and package DNA, have been linked to many types of cancer, but their role in promoting disease has not been clear. Now, for the first time, scientists have found that a change to the structure of a histone can trigger a tumor on its own. More »

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In the News – The New Yorker – Allis

Same but Different: How epigenetics can blur the line between nature and nurture   “Allis walked me to his lab, a fluorescent-lit space overlooking the East River, divided by wide, polished-stone benches. A mechanical stirrer, whirring in a corner, clinked … More »

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Promising class of new cancer drugs causes memory loss in mice

Promising class of new cancer drugs causes memory loss in miceNew research shows that a family of experimental cancer drugs can induce neurological changes in mice. The findings underscore the need for more research to determine whether these compounds can enter the brain, where they potentially might cause side effects such as memory loss. More »

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Discovery links shift in metabolism to stem cell renewal

Discovery links shift in metabolism to stem cell renewalNew research links stem cell metabolism with those cells’ decision to pick a fate or renew themselves. In experiments, exposure to a key metabolite called alpha-ketoglutarate enhanced the renewal of mouse embryonic stem cells. More »

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