Tag Archives: developmental biology

New method allows first look at key stage of human development, embryo implantation

New method allows first look at key stage of human development, embryo implantationAlmost nothing is known about the stage of human development called implantation, when the developing embryo attaches to the uterus. Now scientists have devised a method that replicates implantation in an experimental setting, providing a revolutionary system capable of answering basic questions about our own development. More »

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In the News – Wall Street Journal – Brivanlou

Scientists Grow Embryos for Up to 13 Days Outside the Uterus   “In addition, to both teams’ surprise, the embryos outside the womb were able to ‘self-organize’ or begin to set in motion early development of key body organs without … More »

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New research clarifies how stem cells get activated to produce new hair—and what happens when their regenerative powers wear out

New research clarifies how stem cells get activated to produce new hair—and what happens when their regenerative powers wear outStem cells residing in hair follicles are held in an inactive state for long periods of time. A new study shows that these quiescent periods are essential for maintaining the cells’ rejuvenating activity over time, and clarifies the mechanisms that bring the cells in and out of quiescence. More »

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Widespread skewed expression of mRNA components correlate with fine tuning of protein production

Widespread skewed expression of mRNA components correlate with fine tuning of protein productionIn numerous tissues and genes, the researchers found lopsided ratios in two parts of mRNA transcripts of genes, one of which carries the code for a protein and one that doesn’t. They suspect some of these skewed ratios may help control protein production, particularly in the embryo, but also in the adult. More »

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An embryonic cell’s fate is sealed by the speed of a signal

An embryonic cell’s fate is sealed by the speed of a signalEarly in development, chemical signals tell cells whether to turn into muscle, bone, brain or other tissue. By tracking cells’ responses to signals, researchers found the speed at which the signal arrives has an unexpected influence on that decision. More »

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Using geometry, researchers coax human embryonic stem cells to organize themselves

Using geometry, researchers coax human embryonic stem cells to organize themselvesBy confining colonies of human embryonic stem cells to tiny circular patterns on glass plates, researchers have for the first time coaxed them into organizing themselves just as they would under natural conditions. More »

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