Tag Archives: differentiation

Discovery links shift in metabolism to stem cell renewal

Discovery links shift in metabolism to stem cell renewalNew research links stem cell metabolism with those cells’ decision to pick a fate or renew themselves. In experiments, exposure to a key metabolite called alpha-ketoglutarate enhanced the renewal of mouse embryonic stem cells. More »

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One signal means different things to stem cells versus their progeny

One signal means different things to stem cells versus their progenyWhen researchers shut down hair follicle stem cells’ ability to respond to a protein, the cells began dividing prematurely. Meanwhile, when the same was done to their progeny cells, the fate of these cells shifted. More »

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An embryonic cell’s fate is sealed by the speed of a signal

An embryonic cell’s fate is sealed by the speed of a signalEarly in development, chemical signals tell cells whether to turn into muscle, bone, brain or other tissue. By tracking cells’ responses to signals, researchers found the speed at which the signal arrives has an unexpected influence on that decision. More »

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