Tag Archives: drug resistance

New structural studies reveal workings of a molecular pump that ejects cancer drugs

New structural studies reveal workings of a molecular pump that ejects cancer drugsSometimes cells spit out things we don’t want them to—like medications. Researchers have determined the three-dimensional structure of a tiny pump that expels, among other things, chemotherapy agents. This new knowledge could lead to the design of more effective drugs. More »

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Growth signal can influence cancer cells’ vulnerability to drugs, study suggests

Growth signal can influence cancer cells’ vulnerability to drugs, study suggestsResearchers found that exposure to the signal TGF-β causes changes in mouse tumor stem cells that help them evade a widely used anti-cancer drug. This did not happen to cells that did not receive TGF-β. More »

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