Tag Archives: epigenetics

Researchers create the first model of the DNA ‘replication fork’

Researchers create the first model of the DNA ‘replication fork’This new tool promises to allow scientists to explore the as-yet-unknown details of how cells unzip the double-stranded DNA molecule and replicate it, a process crucial to life. More »

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David Allis, pioneer in epigenetics, to receive prestigious Japan Prize

Allis’s discovery that chemical “tags” bind to specific sections of histone proteins in order to activate or silence nearby genes has ignited the field of epigenetics, a relatively new area of study which explores the inheritance of physical changes that cannot be traced back to mutations in the DNA sequence. The Japan Prize, worth approximately half a million dollars, is among the most prestigious prizes in science. More »

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Influenza “histone mimic” suppresses antiviral response

Researchers have discovered a novel mechanism by which influenza viruses hijack key regulators of the human body’s normal antiviral response in order to slip by it undetected. The results have major implications for our understanding of the biology of the seasonal influenza virus and suggest a possible target for a new class of antiviral and anti-inflammatory drugs. More »

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Experiments decipher key piece of the ‘histone code’ in cell division

The division of one cell into two is one of the most basic processes of life. One of the many tricks involved is the segregation of copied chromosomes to opposite ends of the cell before it divides. New research details for the first time the role of an epigenetic modification to the proteins that package DNA in the fundamental biological phenomenon, known as mitosis. More »

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New science of “epigenetics” advanced by findings reported in Molecular Cell

Scientists have known that some physical changes that are passed on to the next generation can’t be attributed to mutations in DNA alone. Thus a relatively new field of research — epigenetics — has emerged to investigate the inheritance of physical changes that cannot be traced back to mutations in the DNA sequence. More »

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