Tag Archives: Eric Siggia

For biologists studying tiny worms, new technologies make big improvements

For biologists studying tiny worms, new technologies make big improvements Two new technologies are helping scientists understand new aspects of organ and nervous system development in C. elegans. One allows them to image worms developing in a natural environment, while the other makes it possible to track single neurons as the worms grow. More »

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Human embryo discovery wins People’s Choice of Science Breakthrough of the Year

Human embryo discovery wins People’s Choice Science Breakthrough of the YearA revolutionary system that allows researchers to study human embryo development in the lab was chosen by Science magazine readers as the scientific advancement of 2016 that has done the most to benefit humanity, answer long-standing questions, or pave the way for fruitful research.
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New research helps to explain how temperature shifts the circadian clock

New research helps to explain how temperature shifts the circadian clockOne important aspect of the internal time-keeping system continues to perplex scientists: its complex response to temperature, which can shift the clock forward or backward, but cannot change its 24-hour period. New experiments help explain how this is possible. More »

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An embryonic cell’s fate is sealed by the speed of a signal

An embryonic cell’s fate is sealed by the speed of a signalEarly in development, chemical signals tell cells whether to turn into muscle, bone, brain or other tissue. By tracking cells’ responses to signals, researchers found the speed at which the signal arrives has an unexpected influence on that decision. More »

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Eric Siggia joins National Academy of Sciences

Eric D. Siggia, whose laboratory is interested in applying informatics approaches to study gene expression and other biological problems, has been elected to the National Academy of Sciences, one of the highest honors given to a scientist or engineer in the United States. More »

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Simulator allows scientists to predict evolution’s next best move

In evolution, even the slightest beginnings can lead to tools as complex as the human eye. But how? By modeling the steps evolution takes to build, from scratch, an adaptive biochemical network, Rockefeller University scientists have provided a computational answer to one of Darwin’s biggest questions. More »

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Device allows scientists to control gene activity across generations of cells

A group of biophysicists at Rockefeller University has developed a new tool that can control and measure, more precisely than before, the activity of genes and proteins within single budding yeast cells as they divide and multiply. The device may yield new insight into the functioning of regulatory networks. More »

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Sizing cells up: Researchers pinpoint when a cell is ready to reproduce

Like people, cells must reach a certain size before they can reproduce. A collaboration between Rockefeller University biologists, physicists and mathematicians shows how and when cells reach this size requirement, findings that provide researchers with a new quantitative framework to get to the core mechanisms involved in how a cell monitors its size. More »

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New ‘PhyloGibbs’ software helps scientists make sense of DNA

For scientists studying the link between genes and disease, there’s no shortage of information. The challenge is making sense of the data. A new algorithm designed by Eric Siggia’s Rockefeller laboratory may be an important new tool for scientists seeking to extract answers from sequenced genomes. More »

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Noise inner life cells

Within the smoothly operating factory that is the cell, tiny molecular machines carry out their tasks with order and certainty. Or at least that’s what many scientists once believed. More »

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