Tag Archives: gene regulation

C. David Allis receives the 2016 Gruber Genetics Prize

C. David Allis receives the 2016 Gruber Genetics PrizeAllis shares the award with Michael Grunstein of UCLA for identifying the critical role of histones and histone modification in regulating gene activity. The prize is awarded by The Gruber Foundation of Yale University and honors scientists whose work inspires fundamental shifts in knowledge and culture. More »

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Researchers discover new aspect of gene regulation and a possible target for cancer drugs

Researchers discover new aspect of gene regulation and a possible target for future cancer drugsThe expression of about three-quarters of a cell’s active genes is controlled by a process in which the DNA-transcribing enzyme hesitates before going to work. Experiments have identified the complex of proteins that helps restart this enzyme when it stalls, and so helped to explain how some promising cancer drugs work. More »

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C. David Allis wins the 2015 Breakthrough Prize in Life Sciences

C. David Allis wins the 2015 Breakthrough Prize in Life Sciences’Allis is recognized for his foundational research on the unexpected regulation of gene activation by modifications to proteins that package DNA, work with implications for many diseases including cancer. The Breakthrough Prize is worth $3 million, making it the richest prize in the life sciences, roughly double the Nobel Prize. More »

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High blood pressure linked to gene regulation

Genes, as much as treadmills and salads, dictate blood pressure. But new research from Rockefeller University suggests that even the tiniest changes to our DNA can create a predisposition to hypertension. More »

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Rockefeller University researchers identify protein that regulates RNA in nerve tissue

Protein may play a key role in nervous system function Rockefeller University researchers have identified a protein that is responsible for regulating RNA splicing in nerve cells, a process essential for the development and operation of complex nervous systems, such as those found in mammals, including humans. The protein, called Nova-1, is the first splicing factor specific to one kind of tissue to be found in mammals. More »

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