Tag Archives: Hironori Funabiki

New technique reveals a role for histones in cell division

New technique reveals a role for histones in cell divisionResearchers have found that key aspects of cell division, such as the formation of the support structure for the envelope that surrounds the nucleus, depend on the presence of DNA-organizing proteins known as histones. More »

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Hironori Funabiki promoted to professor

Funabiki’s research has pointed to a role for DNA-packaging proteins known as histones in the formation of structures involved in cell division, with implications for understanding and treating disease. More »

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Experiments decipher key piece of the ‘histone code’ in cell division

The division of one cell into two is one of the most basic processes of life. One of the many tricks involved is the segregation of copied chromosomes to opposite ends of the cell before it divides. New research details for the first time the role of an epigenetic modification to the proteins that package DNA in the fundamental biological phenomenon, known as mitosis. More »

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New molecule identified in DNA damage response

Evolution places the highest premium on reproduction, natural selection’s only standard for biological success. In the case of replicating cells, life spares no expense to ensure that the offspring is a faithful copy of the parent. Researchers have identified a new player in this elaborate system of quality control, a gene whose mutation can cause a rare but lethal disease. More »

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Chromosomes are responsible for a critical enzyme’s activation during cell division

The microtubule structures that chromosomes use to migrate to opposite ends of a cell must have impeccable timing: They need to materialize when chromosomes are present, then dissipate when they’re no longer needed. Now, new research suggests that the enzyme Aurora B is the reason that the microtubules show up on time. More »

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Preparing for a safe split

As it prepares to divide, a human cell makes exact copies of all of its 46 chromosomes, so that the two daughter cells each can have a complete set of genetic material. The two sets must separate equally, otherwise the new cells end up with the wrong number of chromosomes. Such problems are common in cancer cells, and have been linked to several types of birth defects. More »

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