Tag Archives: Laboratory of Cellular and Structural Biology

Researchers shed new light on RNA’s journey out of a cell’s nucleus

Researchers shed new light on RNA’s journey out of a cell’s nucleusTo make proteins, cells must export RNA from their carefully guarded nuclei. Researchers have determined the structure of one important component of the restrictive gate through which this cargo must pass, with implications for understanding disease. More »

Tags: , , , , , ,

Parasites reveal how evolution has molded an ancient nuclear structure

Parasites reveal how evolution has molded an ancient nuclear structureThe architecture of the nuclear pore complex is similar in humans and yeast, suggesting that it had been established over a billion years ago. But new research in a simple parasite, the trypanosome, indicates that it has actually been evolving steadily. More »

Tags: , , , ,

New findings help explain how molecules are speedily transported into and out of the cell’s nucleus

New findings help explain how molecules are speedily transported into and out of the cell's nucleusThe nuclear pore complex, a gate into and out of the nucleus, is capable of an impressive feat: allowing large molecules to pass through, both selectively and quickly. Researchers have now identified the molecular mechanism that makes this possible. More »

Tags: , , , , ,

New technique efficiently turns antibodies into highly tuned ‘nanobodies’

New technique efficiently turns antibodies into highly tuned ‘nanobodies’Antibodies’ tiny cousins have many potential uses, but scientists haven’t been able to take advantage of them. However, a new technique may make nanobodies dramatically more accessible for all kinds of research. More »

Tags: , , , , ,