Tag Archives: Laboratory of Membrane Biology and Biophysics

New study resolves the structure of the human protein that causes cystic fibrosis

New study resolves the structure of the human protein that causes cystic fibrosis In order to better understand how genetic mutations give rise to cystic fibrosis, researchers need to map the protein responsible for the disorder. The new structure has led to new insights on how this molecular channel functions. More »

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New structural studies reveal workings of a molecular pump that ejects cancer drugs

New structural studies reveal workings of a molecular pump that ejects cancer drugsSometimes cells spit out things we don’t want them to—like medications. Researchers have determined the three-dimensional structure of a tiny pump that expels, among other things, chemotherapy agents. This new knowledge could lead to the design of more effective drugs. More »

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Study reveals how herpes virus tricks the immune system

Study reveals how herpes virus tricks the immune systemScientists have captured atomic images of the virus that causes cold sores in action. Structural details reveal that the virus inserts itself into another protein, jamming an important immune system pathway that normally allows immune cells to recognize and destroy foreign invaders. More »

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Atomic view of cellular pump reveals how bacteria send out proteins

Atomic view of cellular pump reveals how bacteria send out proteinsWithin the structure of the simple but previously unexamined pump, researchers found a striking feature: a large, water-filled channel, a natural environment for the hydrophilic proteins that must pass through. Their work offers new insight into the mechanics that allow bacteria to manipulate their environments. More »

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