Tag Archives: Laboratory of Molecular Neurobiology and Biophysics

Newly described ion channel structure reveals how excited neurons settle down

The long anticipated structure of an ion channel reveals how excited neurons settle downThe channel, Slo2.2, helps restore neurons’ internal electrical state, and so prevents them from firing at too high a frequency for too long, which has the potential to damage the cells. With the new information about Slo2.2’s configuration, researchers can better understand how it accomplishes this. More »

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Atomic-level view provides new insight into translation of touch into nerve signals

Atomic-Level View Provides New Insight into Translation of Touch into Nerve SignalsAn ion channel responsible for dampening potentially painful sensations uses a never-before-seen mechanism to shut itself off: A lipid from the nearby cellular membrane protrudes into the channel, blocking it. More »

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