Tag Archives: Luciano Marraffini
The enzyme Cas9 is well known for its ability to make precise cuts in a genome. New research reveals a new role for Cas9 in its native bacteria: helping the microbial immune system acquire a memory of an invading virus. More »
By co-opting a system bacteria normally use to defend themselves, researchers targeted and killed off colonies of the antibiotic resistant Staph cells on mouse skin. The treatment left behind the drug-susceptible microbes. More »
Viruses can kill bacteria, or viruses can help the microbes by lending them potentially useful genes. New research shows Staph bacteria have an immune system capable of distinguishing dangerous invaders from potentially beneficial ones. More »
Two Rockefeller University faculty have been awarded the NIH Director’s Transformative Award and three are being given New Innovator Awards.
Experiments in pneumococcal bacteria show how an RNA interference mechanism known as CRISPR can be used to prevent the uptake of genetic material from the environment. Harnessing this mechanism could be a new way to manipulate bacterial evolution in ways that might be medically useful. More »
Rockefeller’s newest faculty member is Luciano Marraffini, a microbiologist who studies how bacterial pathogens modulate the transfer of foreign DNA into their genomes. His work sheds light on how bacteria such as Staphylococcus aureus evolve, including how they gain the ability to resist antibiotic drugs. More »