Tag Archives: mycobacteria

Mutations in a single gene underlie vulnerability to two unrelated types of infections

Mutations in a single gene underlie vulnerability to two unrelated types of infectionsResearchers have identified a surprising case in which defects in a single immune gene render children susceptible to two very different diseases: aggravating, but treatable fungal infections, as well as invasive and potentially fatal bacterial disease. This finding suggests a dual role for that gene, RORC, in human immunity to infection. More »

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Single gene links susceptibility to rare infections with predisposition to autoimmune disease

Single gene links susceptibility to rare infections with predisposition to autoimmune diseaseWhen scientists scanned the brains of patients who lack a particular immune protein, they saw calcium deposits linked with certain diseases that occur as a result of harmful and unnecessary inflammation. More »

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Protein proves vital in immune response to bacteria

Research led by Rockefeller University scientists found that a protein once thought to be mainly involved in antiviral immunity is instead vital to fighting a type of bacteria that cause diseases such as tuberculosis and leprosy.
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