Tag Archives: psoriasis

Psoriasis researchers identify molecular changes responsible for skin discoloration

Two immune system molecules — interleukin-17 and tumor necrosis factor — are increased in psoriasis, leading the immune system to attack a person’s own skin cells. Scientists found that these molecules disrupt the pigment production of patients’ melanocytes, and are responsible for the dark spots that psoriasis leaves behind. The results could bring about new treatments for pigmentation changes in this and other skin conditions such as eczema and acne. More »

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New clinical study probes how light fights psoriasis

A new clinical trial under way at The Rockefeller University Hospital will literally shine light on psoriasis in hopes of finding out exactly how phototherapy works. Narrowband ultraviolet light B (UVB) therapy is known to kill off T cells, which are partly to blame for the inflammation caused by the disease. Exactly how it does that remains a mystery. More »

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Newly uncovered cells may be critical in psoriasis


In a study that could change researchers’ understanding of the skin disorder and suggest potentially powerful new drug targets, Rockefeller University scientists have found that the source of psoriasis may lie in a specific population of inflammatory dendritic cells. More »

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Psoriasis lesions loaded with newly discovered immune cell

For years, scientists had been trying to fight psoriasis by concentrating on a type of immune cell called Th1. But new research points to the Th17 cell as being a key player in the disease, and a potentially better target. More »

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Recently discovered cell is unexpected player in psoriasis

The psoriasis drug etanercept has had a high success rate, but its mechanism was largely unknown. Now, by studying patients’ immune reaction to the drug, Rockefeller University researchers have found that a newly discovered immune cell — the Th17 cell — may be playing an unexpected role in the disease. More »

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Newly discovered immune cell partially responsible for psoriasis

In a discovery that may help shape new treatments for psoriasis, scientists at Rockefeller University have found a new type of immune cell that may be critical in producing inflammation and tissue damage in the skin. More »

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