Tag Archives: RNA
New research reveals how cells sort out the RNA molecules destined to become gene-regulating microRNAs by tagging them. Because microRNAs help control processes throughout the body, this discovery has wide-ranging implications for development, health and disease, including cancer.
Darnell will direct all aspects of the NYGC, including its scientific and research activities, and the recruitment and development of a world-class scientific team in genomic research and medicine. Founded in 2010, the NYGC will be one of the largest genomics research facilities in North America, integrating sequencing, bioinformatics and data management. More »
It would seem a stunning improbability for a whirlwind to spin through a junkyard and leave behind a fully assembled jumbo jet. This colorful metaphor by astronomer Fred Hoyle points out the difficulties encountered by scientists when they try to understand how life could have emerged billions of years ago. Researchers at Rockefeller University now show how crude pieces of a genetic system could self-assemble and generate the rules of life’s most fundamental code. More »
The university promotes a biochemist who researches RNA interference (RNAi), the process by which small RNA molecules interfere with gene expression. More »
The postgenomic era has taught us a big one: That the measure of human complexity has less to do with how many genes we have as it does with how we process them. Now, Rockefeller University scientists offer, for the first time, a genome-wide view — from the first chromosome to the last — of how differences in RNA can explain how a worm and a human can each have 25,000 genes yet be so different. More »
Using the structure of the protein σ28 bound to its inhibitor as inspiration, a new structural study finds that this gene activator can also inhibit itself from binding to and expressing the wrong gene at the wrong time. More »
Protein may play a key role in nervous system function Rockefeller University researchers have identified a protein that is responsible for regulating RNA splicing in nerve cells, a process essential for the development and operation of complex nervous systems, such as those found in mammals, including humans. The protein, called Nova-1, is the first splicing factor specific to one kind of tissue to be found in mammals. More »