Tag Archives: Shai Shaham

For biologists studying tiny worms, new technologies make big improvements

For biologists studying tiny worms, new technologies make big improvements Two new technologies are helping scientists understand new aspects of organ and nervous system development in C. elegans. One allows them to image worms developing in a natural environment, while the other makes it possible to track single neurons as the worms grow. More »

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Rockefeller’s annual science festival draws hundreds of young explorers and their families

Science SaturdayOn a recent Saturday, the Rockefeller campus was transformed into a vast science exhibit with more than 35 interactive stations. Each year, this popular event draws families from across New York City to experience the authentic process of science. More »

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A common brain cell shapes the nervous system in unexpected ways

A common brain cell shapes the nervous system in unexpected waysGlial cells nourish, protect, and support neurons, but their role is far from passive. A new study shows how they can change the shape of nerve endings and distinguish between the different types of neurons they encase. More »

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A newly discovered way for cells to die

A newly discovered way for cells to dieIn studying how worms develop from larvae into adults, scientists have discovered a previously unknown process in which cells are programmed to die. The findings might have implications for understanding some diseases, including neurodegenerative disorders. More »

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Shai Shaham and Sean Brady receive promotions

Shaham, head of the Laboratory of Developmental Genetics, studies the control of programmed cell death during animal development and the roles of glial cells in nervous system development and function. He has been awarded tenure and promoted to professor. Brady, head of the Laboratory of Genetically Encoded Small Molecules, looks for new genetically encoded small molecules from bacterial sources, chemicals that may play a role in the development of new pharmaceuticals. He has been promoted to associate professor.

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Shaham and Chalasani named winners of 2009 Blavatnik Awards

Associate Professor Shai Shaham and Postdoctoral Fellow Sreekanth H. Chalasani, who were named finalists in the third annual competition in September, were honored last night with six other winners at the New York Academy of Sciences’ Science and the City Gala. More »

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Two Rockefeller scientists named finalists for Blavatnik Awards for Young Scientists

Associate Professor and head of laboratory Shai Shaham and Postdoctoral Fellow Sreekanth H. Chalasani are finalists in the third annual competition administered by the New York Academy of Sciences. More »

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Scientists show how a neuron gets its shape

For the brain to work, neurons have to be connected in the right places. Now, new research shows that rather than growing like the branches of a tree — extending outward — certain neurons work backward from their destination, dropping anchor and stretching their dendrites behind them as they crawl away. More »

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Without glial cells, animals lose their senses

When it comes to picking up and bringing information into the brain, sensory neurons have always put on a star performance. But now they’ll need to share the credit. In groundbreaking research to appear in the October 31 issue of Science, scientists reveal that while neurons play the lead role, a second type of cell, the glial cell, pulls the strings behind the scenes. The work not only lifts a long-ignored cell out from obscurity but shows how it is a critical member in shaping sensory experience. More »

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Glia guide brain development in worms

When the stakes are high, communication is crucial. In a landmark discovery, Rockefeller University scientists have identified a system in the C. elegans brain that allows them to study how brain cells, neurons and glia, talk to each other — the dialogue that shapes and guides the developing brain. More »

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New method exploits old mechanism to turn genes on and off at will

When body heat rises to dangerously high temperatures, the heat shock response protects proteins from irreversible damage. Now, new research in C. elegans roundworms exploits this ancient mechanism to control when and where genes are expressed, an ability that helps determine which cells require the expression of certain genes during different stages of development. While existing techniques enabled scientists to achieve this feat, this new method provides them with the same information in a fraction of the time. More »

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For dying cells, timing is everything

Conventional wisdom suggests that cells are at all times balanced precariously between life and death, with proteins that could kill the cell poised to strike at a moment’s notice. While this is certainly true in some cases, new research from Rockefeller University shows that it is not universal, and that several layers of regulation control cell death. More »

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Researcher discover new cell death program

Though caspases are the accepted executioners of the cell world, new research shows that they may not be the only ones. By following the life, and death, of one cell, Rockefeller University researchers discover a new type of cell death. More »

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Worming our way into the brain

Rockefeller scientists find that studying glial cells in the roundworm C. elegans may provide insight into a variety of human brain diseases. More »

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