Tag Archives: St. Giles Laboratory of Human Genetics of Infectious Diseases

Mutations in a single gene underlie vulnerability to two unrelated types of infections

Mutations in a single gene underlie vulnerability to two unrelated types of infectionsResearchers have identified a surprising case in which defects in a single immune gene render children susceptible to two very different diseases: aggravating, but treatable fungal infections, as well as invasive and potentially fatal bacterial disease. This finding suggests a dual role for that gene, RORC, in human immunity to infection. More »

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Leslie Vosshall and Jean-Laurent Casanova elected to the National Academy of Sciences

Jean-Laurent Casanova and Leslie Vosshall elected to the National Academy of SciencesVosshall, who investigates how sensory stimuli are perceived and processed, and Casanova, who studies the genetics of infectious disease susceptibility in children, are among the new members and foreign associates to be inducted into the Academy in 2015. With Vosshall and Casanova’s election, Rockefeller now boasts 36 members or foreign associates of the National Academy of Sciences among its current faculty.

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Genetic mutation helps explain why, in rare cases, flu can kill

Genetic mutation helps explain why, in rare cases, flu can killA small number of children who catch the influenza virus fall so ill they end up in the hospital even while their family and friends recover easily. New research from Rockefeller helps explain why: a rare genetic mutation that prevents the production of a critical protein, interferon, that is needed to fight off the virus. More »

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Jean-Laurent Casanova to receive 2014 Robert Koch Award

Jean-Laurent Casanova to receive 2014 Robert Koch Award Casanova is honored for his work on host genes and their products in infectious diseases. His lab is interested in why some children develop severe infectious diseases after coming into contact with certain pathogens, while most other children do not. More »

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Brain displays an intrinsic mechanism for fighting infection

Researchers in the St. Giles Laboratory of Human Genetics of Infectious Diseases have shed light on how a genetic defect leaves some children susceptible to a rare and damaging brain infection and have found evidence of an intrinsic immune mechanism in the brain that fights the viral infection in healthy people. More »

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Jean-Laurent Casanova honored with Belgium’s highest scientific prize

Jean-Laurent Casanova has received the 2011 InBev-Baillet Latour Health Prize, Belgium’s most important scientific prize, for his pioneering work on the identification of genes that predispose for human infectious disease. More »

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