Tag Archives: Stress

Resistance to antidepressants linked to metabolism

Resistance to antidepressants linked to metabolismRecent findings by a Rockefeller University team might offer new clues about why some patients don’t respond to antidepressants. While investigating resistance to treatment in rats, the scientists uncovered changes in genes that control metabolism. More »

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Researchers find new signs of stress damage in the brain, plus hope for prevention

Researchers find new signs of stress damage in the brain, plus hope for preventionNew research shows that when mice experience chronic stress, neurons within part of their brain’s fear and anxiety center, the amygdala, retract. It also suggests how such changes could be prevented. More »

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Newly discovered windows of brain plasticity may help with treatment of stress-related disorders

Newly discovered windows of brain plasticity may help with treatment of stress-related disordersEven under repeated stress, the brain maintains the potential to adapt and recover. Researchers have shown how changes in gene expression cause these transitory opportunities to open up. Their results suggest well-timed treatment could change the trajectory of a brain suffering from depression or other disorder. More »

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In the News – ABC – McEwen

Ebola: A crash course in fear and how it hurts us   “Bruce McEwen, a neuroscientist who studies stress at Rockefeller University in New York, said the fear can lead people to change their lifestyle, making them isolate themselves, lose … More »

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Research hints at why stress is more devastating for some

Research hints at why stress is more devastating for someSome bounce back from stress, while others struggle with it, even developing anxiety and depression as a result. In experiments with mice, researchers have revealed the molecular origins of this so-called stress gap.
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In the News 7/16/14

Dialing Back Stress With A Bubble Bath, Beach Trip And Bees   “Stress raises our heart rate and ramps our immune systems to prepare for injury and danger. ‘The problem is if we don’t turn those responses off efficiently when … More »

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Acute stress improves working memory, research suggests

Stress is no fun. Chronic stress can ruin your health. But the body’s response to troubling situations is not without benefit. New research shows that after a brief encounter with a stressful scenario, the resulting acute stress actually makes you smarter. Or at least it improves the working memory of rats by ramping up production of neurotransmitters in the prefrontal cortex, a key region of the brain controlling emotion and cognition. More »

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Protein found linking stress and depression

Unrelenting stress can both cause and exacerbate a host of psychological disorders, but researchers don’t know exactly how. Pushing forward a mechanistic explanation of how stress works the brain over, scientists at Rockefeller have identified an important piece of a cell receptor that is behind anatomical changes in parts of brains under stress. The particular piece, or subunit, has been recently implicated in major depression, response to antidepressants and also susceptibility to suicidal ideation, in the STAR*D trial, the largest study of antidepressant-treatment response conducted to date. More »

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Gene linked to anxious behavior in mice

Mice and men are different in many ways, of course, especially when it comes to the psychological. But new research linking a gene in mice to anxious behavior raises the prospect that we get some anxiety disorders from a piece of DNA we share with the little mammals. The gene, Lynx2, alters neurotransmission in parts of the mouse brain associated with anxiety. The same parts are associated with anxiety in humans. More »

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Stress disrupts human thinking, but the brain can bounce back

Med school students prepping for their boards and rodents digging for food have a bit of psychology in common: Stress hampers their nimbler thinking abilities. A new neuroimaging study, building on earlier rodent research, shows that stressed-out men, like rats, have a hard time shifting their attention from one task to another. But the work holds good news too, for both rats and humans: Their brains are resilient. Less than one month after the stress disappears, the quick thinking returns. More »

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In mice, anxiety is linked to immune system

In groundbreaking research that advances the knowledge of how the two most complicated systems in the body are linked, researchers reveal that immune cells in the brain directly influence how mice normally behave in stressful situations. The work is the first ever to genetically link mast cells to anxiety and opens new doors for drugs that target immune cells in the brain to regulate emotions. More »

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Stress response in the brain relies on a blood-thinning protein

Our ability to learn from stressful situations allows us to try to avoid them in the future. New research by Rockefeller University scientists shows that a protein called tPA in the hippocampus — a region of the brain responsible for memory, learning and fear — plays an essential role in this learned fear response and could be involved in depression. More »

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Chronic stress effects attention by altering neuronal response in the brain

Anxiety and depression can make a person feel as if he’s battling his own brain, complete with wounds and scars. Traumatic events — war, divorce, the death of a loved one — can trigger these disorders, and scientists are just beginning to clarify the biological connection. Now, working neuron by neuron, researchers have found that life experiences actually appear to change the length and complexity of individual brain cells. More »

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Genetic ‘stress response’ may explain how bacteria resist drugs

Bacteria have a nasty habit of developing resistance to even our most powerful pharmaceuticals. But by tracking the staph infection of a single patient during a course of antibiotic treatment, Rockefeller University scientists have discovered new clues to how bacteria evolve resistance. More »

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Neurons in the brain change shape when stressed

Rockefeller University scientists are inching closer to understanding how long-term stress can change an area of the brain responsible for learning and memory. In a finding that may have implications for the treatment of post traumatic stress disorder and severe depression, they report that an animal’s response to chronic stress is at least partially dependent on an enzyme called tissue plasminogen activator, or tPA. More »

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Single stressful events bring about gradual change in brain structure

Research in rats shows that chronic, uncontrollable stress leads to gradual changes in brain structure over weeks. Yet, even a single acute stress also causes a structural change in the rat’s brain, not immediately but over days, along with higher levels of anxiety. These results may shed light on what is happening in the human brain during anxiety disorders and depressive illness. More »

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“Stressed out” by living and working in NYC?

Car alarms. Traffic jams. Job layoffs. These almost daily events are among the reasons that New Yorkers often feel stressed out. But while many people can identify what triggers their stress, they may not understand how it affects their bodies and what they should do to cope. Answers to these and other questions will be discussed by experts at a public lecture titled “Stress: A New York State of Mind,” at 7 p.m., Tuesday, April 29, in Rockefeller University’s Caspary Auditorium (York Avenue at East 66th Street). More »

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More Studies Shed Light on How Prozac Works

Nobel laureate Paul Greengard, Ph.D., and other Rockefeller University scientists have illuminated, in laboratory mice, new details of the complex chemical interaction in the brain that is generated by Prozac, the widely prescribed drug for depression. More »

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A Little Stress May Have Big Benefits for Health

Rockefeller University researchers have shown that brain hormonesrally immune cells in response to stress. The findings, reportedin the Feb. 2 issue of the Proceedings of the National Academyof Sciences (PNAS), contradict the widely held notion thatall stress is bad for health and provides a basis for understandingthe role of stress in health and disease. More »

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From the Center for the Advancement of Health: Stress: It’s Not Just All in Your Head

Please refer to the following link: http://www.cfah.org/